Liv52 doesn't have useless milk thistle which apparently raises SHBG and makes orals absorb less efficiently. Just going off bro science. Read a few studies and that was enough to stop me from using it. Milk thistle is shit. Liv52 or "LiverCare" up in Canada is THE shit.
It blocked AR or reduced AR number (forget which) in the prostate. Doubt it reduces the effectiveness of a cycle any.
If one is taking liver toxic orals, does taking LIV 52 at the same time offset some of the negative effects?
Theoretically it might. Some research says it has anticholestatic properties and cholestasis is what could lead to liver damage when on oral steroids. I'm sure it wont hurt to add a few hundred mg of Milk Thistle to the regimen.
To me ursodesoxycholic acid (or the TUDCA that Thermolife sells) looks like the best liver protective supplement. Some phospholipid supplements could be a good idea as well.
Glutathione boosters, like NAC and R-ALA wouldn't hurt either. I saw one abstract that said Anadrol depleted hepatic glutathione.