A Body built with heavy weights and without MASSIVE amounts of Drugs is a Body you can have for LIFE.Unlike the Pros who go off the source and end up looking like a school boys.FFS 
Yes, bodybuilding with drugs and bodybuilding without are far different.
With drugs, gains come more quickly, but are temporary and training is higher volume and more frequent than without.
Without, gains come more gradually, but are fairly permanent and training is less volume and less frequent than with.
(This is assuming both are training with high intensity, of course.)
Bottom line, people who are not taking drugs should be careful about taking training advice from those who do take drugs.