I asked if the amount/type of receptors are the sole determining factor? How would you explain it?
No, not sure if I have seen Renee Toney.
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Females are on general significantly smaller than males. So a heavily developed female with great genetics for building muscle, like Iris Kyle, is going to be a lot bigger than men who don't train, but isn't going to come close to a heavily developed male with great genetics for building muscle like Victor, Branch etc.
Saying that she could probably do very well in her weight class at the mens nationals.