I'm in SW Florida - Estero/Naples.
I lived in Sarasota right off Siesta Key for almost 2 years... it's beautiful.
I spent last weekend in the FL Keys (Islamorada)... it was even better.
I have vacationed in Orlando quite a few times, it's nice.
The everglades might be my favorite spot - just miles of swamp and lots of critters.
I've lived in a few cities here, been to others. Just like anywhere else, the bigger cities (and the smaller ones too) can be pretty ghetto. But the outlying areas as nice. Really depends where you are in Orlando and what you like to do.