questions on pharmacology of insulin

[flinstones1]

1.Would there be any benefit of taking insulin at every meal as in 2-4iu , just to decrease protein breakdown while bulking? Let me clarify, assuming your pancreas still functions normally and are  a nondiabetic, would low doses of exogenous insulin still be superior to what your body naturally makes?

2. Also I would think there would be some possible health benefits associated with this, as blood glucose never really gets too high by taking exogenous insulin, your pancreas never really needs to release any insulin like it normally would. and since  we all know the dangers of high blood sugar and the risk it has on one's health it seems logical that a healthy person (nondiabetic) could benefit from taking exogenous insulin for anti aging and health purposes As well as using food more efficiently

3. One last thing, how important is insulin necessary for muscle growth in the first place? It's often thrown around alot, but if Amino acid uptake does not require insulin why is it so important to grow muscles larger? or is it?

thanks

[chess315]

im kinda leaning torward that there would be. I have heard old protocols that called for 3-4ius 3 times a day

[tbombz]

its not very important , not at all.

check out all the physiques built between 1970 and 1995.

sergio olivia, arnold, serge nubret, franco columbo, lee haney, early dorian yates, sean ray....

none of those guys used insulin.

[chess315]

its my understanding they have expermented with it since the mid 1980s tim belknap trained at golds with the old crew and he said he thinks some of the guys back expermented around. Also it was noted that people on insulin who worked out had more muscle mass around that period to. I agree you can get very big without it though

[flinstones1]

its my understanding they have expermented with it since the mid 1980s tim belknap trained at golds with the old crew and he said he thinks some of the guys back expermented around. Also it was noted that people on insulin who worked out had more muscle mass around that period to. I agree you can get very big without it though

It's just too cheap not to abuse use 

[dustin]

It's just too cheap not to abuse use 

Agreed.

I've read lots about insulin but I'm not satisfied with my understanding of it. I'm going to try my hand at using it again. It'll be a lot more methodical and structured usage though. I've finally got the epic leans but I want to be as lean and dry as possible without the use of diuretics before I use slin again.

Will use a lot bigger doses but make sure not to get fat or bloofy though. It's a crazy drug and I think people just need to use it correctly. I know a few guys who are jacked as fuuuuuuccckkkk and they just use enough to get them where they need to be. Pros are too far gone when it comes to abuse not to just fill the fucking syringe all the way up. If they're going to pin, it's always going to be a full syringe of this or a handful of that.

[flinstones1]

Agreed.

I've read lots about insulin but I'm not satisfied with my understanding of it. I'm going to try my hand at using it again. It'll be a lot more methodical and structured usage though. I've finally got the epic leans but I want to be as lean and dry as possible without the use of diuretics before I use slin again.

Will use a lot bigger doses but make sure not to get fat or bloofy though. It's a crazy drug and I think people just need to use it correctly. I know a few guys who are jacked as fuuuuuuccckkkk and they just use enough to get them where they need to be. Pros are too far gone when it comes to abuse not to just fill the fucking syringe all the way up. If they're going to pin, it's always going to be a full syringe of this or a handful of that.

thanks Dustin. Also one thing I notice, when I started taking insulin steroids definitely seem to work better. Or quicker for that matter,  I did some research and found that insulin increases the binding ability of anabolic steroids to the androgen receptor as well as increasing igf levels.

[dustin]

thanks Dustin. Also one thing I notice, when I started taking insulin steroids definitely seem to work better. Or quicker for that matter,  I did some research and found that insulin increases the binding ability of anabolic steroids to the androgen receptor as well as increasing igf levels.

Something special definitely happens. The answer is somewhere in between the medical journals and the bro science. I  can't wait to use slin again. I never used enough of it long enough to see any changes, but I could tell there was a storm brewing. I'll just make sure I don't end up with fat marbled everywhere like the bloofy messes on stage these days.

[claymore]

Insulin works and it works VERY WELL, the key to slin usage is MODERATION, most confuse that word with ABUSE !!

[chess315]

the mid 1980s I belive is when studies on diabetics showed people using insulin tend to carry more lean muscle at that point it would have been open game. and tim belknap training in venice where everyone else trained at that point would have spread it to. Not that he was the best look bodybuilder but he is kinda of the missing link between the 1980s and now you can look at him and tell that something is going on different in his body then his peers. I think another reason people dont see results with it they give up to quick after a month or so. Gh may make it work better but it should work with out it it did for the diabetics who carried more muscle mass why wouldnt it for a bodybuilder? Even if it only added 10lbs to a steroid users frame that is enough to make a huge impact. That take you from as gh15 say 5,6 185 6% to 195 6%

[flinstones1]

Tbombz this explain why insulin at low doses doesn't do shit fro 95% of people? Low doses are just not enough to cause an osmotic response in muscle tissue.

Insulin is predominantly a storage hormone in that it initiates a cascade of cellular events that result in up-regulation of cellular nutrient content. It obviously goes without saying then that supraphysiological plasma levels of insulin result in supraphysiological cellular levels of nutrients. This in itself allows for a highly anabolic effect known as an osmotic response. A cellular osmotic response is nothing more than an increase in water and growth potentiating nutrients intracellularly that has an effect similar to increasing the amount of air in a balloon. More air in the balloon means a larger balloon. More water and proportionate growth nutrients means a larger cell. Interesting enough is the fact that this also triggers another survival mechanism that tells the stretched cell wall to increase in thickness to accommodate the osmotic response. This is due to an up-regulation in localized IGF-1 and MGF production and the synergistic response initialize. Oh ya. That is anabolism in the form of hypertrophy. Unfortunately, insulin is quite anabolic to fat cells too.

[flinstones1]

the mid 1980s I belive is when studies on diabetics showed people using insulin tend to carry more lean muscle at that point it would have been open game. and tim belknap training in venice where everyone else trained at that point would have spread it to. Not that he was the best look bodybuilder but he is kinda of the missing link between the 1980s and now you can look at him and tell that something is going on different in his body then his peers. I think another reason people dont see results with it they give up to quick after a month or so. Gh may make it work better but it should work with out it it did for the diabetics who carried more muscle mass why wouldnt it for a bodybuilder? Even if it only added 10lbs to a steroid users frame that is enough to make a huge impact. That take you from as gh15 say 5,6 185 6% to 195 6%

is there any proof that insulin dependant diabetics carry more muscle mass than nondiabetics? Afterall they are using physiological doses of it.  alot diffrent than slamming 15iu postworkout lol.

[Meso_z]

Doesnt answer to the topic but why the hell would someone need insulin if hes not a pro.

Why dont you stick to aas and gh, hell even only on aas.

Its like being a natural and rushing into steroids for "rapid gains" without first putting effort in the gym.

[tstmaniac]

Doesnt answer to the topic but why the hell would someone need insulin if hes not a pro.

Why dont you stick to aas and gh, hell even only on aas.

Its like being a natural and rushing into steroids for "rapid gains" without first putting effort in the gym.

You speak the truth. Good post

[Meso_z]

You speak the truth. Good post

I think its common sense....why take the fucking risk..

I see this in couple guys in my gym who look like NOTHING!!!

After the workout they rush into the locker lrooms shooting insuling with carbs in a shake or something, while getting out and then back in...always nervous along with their buddy...rofl.

 im not familiar with those methods...I dont know shit about using insulin neither i do care to learn. as if I didnt have enough of this ..i should "pin" right after training...like a junkie.jeez get a life.

not worth it.

[whitewidow]

id stay away from insulin unless you are a pro making some good money why risk your health. it works very well but you really have to know what your doing. Test,Deca,HGH, Insulin and Tren is enough to turn someone into a monster if they know how to use everything right

[dustin]

C'mon, guys. You're perpetuating the stigma that insulin, for whatever reason, is some sort of mythical drug which is outside our realm unless we're IFBB pros.

Do you really think those cum knocking drug abusers have some sort of fantastic knowledge which we can never fathom? Sorry, but I don't buy it. Some douche bags that brought it to light on the forums always spoke about it as though it was shrouded in mystery. Just like when any other drug hit the scene, the people behind it always acted as though it's use can only be through their secret covenant which closely guards the secrets of it's sorcery. 

Do you guys really believe that shit? Just because someone can go into a diabetic coma using insulin, doesn't mean that it's some pixie dust that only muscle faeries from Schmoeville can utilize. There are immediate dangers which are present, yes, but all things considered it's not THAT much more dangerous as AAS and other PEDs. These are the same low brow tactics that faggy little weed dealing wannabes try spitting when you want to buy a bag. You guys are pretty stupid if you still fall for that shit. No offense.

[Meso_z]

C'mon, guys. You're perpetuating the stigma that insulin, for whatever reason, is some sort of mythical drug which is outside our realm unless we're IFBB pros.

Do you really think those cum knocking drug abusers have some sort of fantastic knowledge which we can never fathom? Sorry, but I don't buy it. Some douche bags that brought it to light on the forums always spoke about it as though it was shrouded in mystery. Just like when any other drug hit the scene, the people behind it always acted as though it's use can only be through their secret covenant which closely guards the secrets of it's sorcery. 

Do you guys really believe that shit? Just because someone can go into a diabetic coma using insulin, doesn't mean that it's some pixie dust that only muscle faeries from Schmoeville can utilize. There are immediate dangers which are present, yes, but all things considered it's not THAT much more dangerous as AAS and other PEDs. These are the same low brow tactics that faggy little weed dealing wannabes try spitting when you want to buy a bag. You guys are pretty stupid if you still fall for that shit. No offense.

I see your point..its all good. 

In my opinion..it simply does not worth the effort..its my opinion since I know shit about insulin usage I might be wrong.

[lesaucer]

i tried as high as 150ius for a few day with zero sides. stopped because it blow you up yes but the retention is crazy and it ruins the lean face because of all the carbs you have to eat so you dont go hypo, but im 100% sure if you stick with it for 1-2 months you can get absolutely huge, i gained like 10-15lbs in 5 days when i tried it...

[flinstones1]

i tried as high as 150ius for a few day with zero sides. stopped because it blow you up yes but the retention is crazy and it ruins the lean face because of all the carbs you have to eat so you dont go hypo, but im 100% sure if you stick with it for 1-2 months you can get absolutely huge, i gained like 10-15lbs in 5 days when i tried it...

haaha what a pussy.

[dyslexic]

The only reason Tim Belknap discussed the effects of insulin with his bodybuilding comrades is because he was a Type 1 Diabetic. He and his friends noticed a more "pronounced' effect on his physique. He may very well have been the pioneer of Insulin use in Pro BB circles.