What are his "peeing side-effects?"
Does he have a kidney condition, prostate problem, or some other urinary issue?
Anyway, concerning your question about supplements...
According to user feedback, N.O.-Xplode isn’t what it was when it came out years ago.
For what it’s worth, I tried it then and still wasn’t impressed with it.
Creatine, however, has withstood the test of time - still included in many quality workout supplements.
It is certainly worth glancing over the sticky’s PL has made - particularly as it relates to types, timing, etc.
Replenishing ATP stores, hydrating muscles, and facilitating protein synthesis are all effective mechanisms for improving exercise performance and long-term muscle growth.
The “cell-volumizing”/intra-cellular bloat is often a pleasant short term visible effect for those who like instant gratification, which may provide a bit of reward and motivation.
A lot of people who turn to supplements need that.