I'm picking Cowboy to win this. It's a kick boxer vs a boxer, both with solid BJJ. Maybe Cowboy will fix Nate's lithp once and for all.
Fight of the Night right here.

Heavyweight bout: Brock Lesnar vs. Alistair Overeem If Lesnar comes in healthy he will win. But his health problems and long layoff are a big ?.
Lightweight bout: Nate Diaz vs. Donald Cerrone Cowboy should win this, but I think Nate will upset him.
Welterweight bout: Jon Fitch vs. Johny Hendricks
Light Heavyweight bout: Vladimir Matyushenko vs. Alexander Gustafsson - who cares
Featherweight bout: Nam Phan vs. Jimy Hettes