Not me really. I've used as much as 50mg a day as studies have shown that even this doesn't bring you below normal range of estrogen even off cycle. I get high estro/bloat, though, easily, as I was receiving trt a few years back and on just 200 mg of cyp a week my estrogen was quite high. I would also say that I am beginning to think that the aromasin I use isnt all that good, because it seems as if when I switched brands due to cost i can use a lot of this kind and still not get the same effects at 50mg as the other brand I was using at 25 mg. But have gone as high as 37.5 mg with the legit kind and liked it, personally.