I've found that 2-3 glasses of wine... a few nights a week... really slows me down.
I've found that ZERO wine is fine, but I get all tight in the chest, I get a little annoyed with things, I get frustrated.
I've found that ONE glass of wine - and just one - maybe 2-3 nights a week is great for lowering the blood pressure, letting me unwind and kick back for an hour (i'm typically working or moving 24/7 when i'm not sleeping).