I don't really take any pre-work out supplements nowadays, mainly just drink some BCAA's during my work out and have a 20 oz bottle of coke zero a few hours before with my meals
I do have a tub of NO Xplode at home that I save for days where I'm UBER UBER tired and really struggling to go to the gym, but honestly never really feel the need to use it, its very rare when I do. I used to love drinking the RTD NaNo Vapor before and during my work out that shit felt fucking potent.
But for the most part, I get good sleep at night, pretty consistent with my diet, and even without the pre-work out drinks I don't feel any lack of energy while I'm in the gym. I still get awesome pumps etc. So I don't find pre work out supplements to be essential or anything. Sure they could help - some people swear by them, and if you feel an improvement, by all means use them, some say it improves flushing nutrients to your muscles, etc.
Do I feel a difference whenever I use them? Not in particular, sometimes I do, sometimes I don't.... like I said I almost always have lots of energy while I'm at the gym and getting very good pumps, with sore muscles the next day, regardless of what I'm taking.