Besides everything else that is physically repulsive, you haven't even considered the mental issues. If they are even 1/10th of what each of her parents have, or even brother Jack....she is a basket case who is only going to get worse.
Sad but true. She has no role models except for an eccentric hypochondriac mother and a senile decrepit old wasted father....
What can she possibly do for the sake of resilience?