Don't exceed the 4 gram daily limit.
Each tablet is 500mg, do not exceed 8 tablets in 24 hours.
Remember Aspirin is an NSAID and inhibits both
Cox-1 and
Cox-2 (enzymes directly involved in prostaglandin synthesis).
The Cox-1 inhibitory effect of Aspirin can be seen in:
GI tract protection, Renal function and platelet aggregation. (In other words, it reduces the protective properties of the GI tract, provides a decline in renal function and reduces platelet aggregation)
The Cox-2 inhibitory effect of Aspirin can be seen in:
Pain, fever and inflammatory processes. (In other words, it reduces pain, fever and inflammation)
Take too much Aspirin over time and you will possibly have: gastric ulcers, kidney function decline or failure, decline in platelet aggregation (which is what leads to prolonged bleeding) and slowed healing processes that can lead to prolonged recovery over the course of an injury, disease or infection.
*As an added tidbit, Aspirin does not actually thin the blood, that is a common urban myth. There is no pharmacological action by way of Aspirin in actually reducing the viscosity of the blood*
Here is your guide for your maximum daily dose, take a look at the label on that bottle of Bayer Aspirin Advance:

For extra reading material based on peer-reviewed medical literature, take a look at these sites:
http://www.nlm.nih.gov/medlineplus/druginfo/meds/a682878.htmlhttp://www.mayoclinic.com/health/daily-aspirin-therapy/HB00073"
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