I have known some really big guys - mostly body builders that did the 1 body part a week thing - split M-F, and looked pretty good- they were natural, too. Not freaks, but really good physiques - 25'' quads, 18'' arms etc.. and the guys I am thinking of right now were in the 225- 230 range, they are definitely OCD though when it comes to the gym - they said 3 x a week wasn't enough for the "next level"
Honestly though, I don't know how you wouldn't burn out going balls to the wall 5 days a week, but these guys do it year after year
I have also known a few powerlifters that trained pretty much 5 x a week, these were specialists though - one guy was a bencher and the other a squatter, they both swore high volume training was by far the best way to go for strength gains, not so much size though.