If you are in the Miami area, stick to SoBeach. If you find yourself in Overtown, especially near sundown, run, don't walk back to South Beach. That place ain't no place for an out of towner unless you are coming heavy.
If you can, come up I95 about 60 minutes to Delray Beach, specifically Atlantic Avenue. First, because many folks from MIA are coming up there because of the club/restaurant scene. Second, if it's a weekend night, you will DEFINITELY seen Jason Genova ILSing down the Ave. A pic of Irish and Jason would be epic.