it depends.
normaly you lose not so much bc upping the dosage from some point wont grant diametrical results.ie you dont gain double from going from 500-1000mgs.
but you sure do gain about double when going from 250 to 500.thats even backed by studies.
you go more or less back to that what you looked on the particular dosage.n 500weekly,will always look kinda the same once maxed out, on 1000week,will alwyas look more or less same etcetc.
howver, when one did huge dosages for a while, they will be able to keep suprisingly much mass on much less gear than before.
but this is mostly due to the effect that many respond very well to low-moderate doses and then when they up the dosage much more, the gains wont be as good as expected by calculations.
going off, you lose plenty.going off hrt, its not bad, but bad enough.
going off a gramm will be bad.
going of 2gramms is like jumping of a cliff.