first 'failure'?
when my pharmacy in Tijuana was "raided by police" in Oct '04 and my biz partner, 2 employees, and employee's 12yr old niece were cuffed and hooded and taken away on a Saturday morning... same morning I was supposed to be there but for whatever reason I didn't go (I'd probably drank too much already and was too lazy to go drop off orders).
I showed up next day (sunday) to find my door's closed and locked (with a different padlock) at 10am (we should've been open at 9am).. where I waited for over an hour 'till the old man from the pharm next door came out and asked what I was doing there and told me what happened.
never heard from my biz partner or anybody else after that... I doubt they were arrested, and probably ended up in a 55gal drum in the desert.

*poof* and my 33% stake in the biz was gone. lol
went down a few weeks or so later and saw that somebody else was operating it, and obviously didn't know who I was. I bought a bottle/pack of valium and used the back room to stash the pills in the seams of my pants and overheard a lady in what used to be my office mentioning the name "paul" over and over... long story short, it was the ex-wife of Paul Borrenson. lol... I didn't bother asking what the fuck was she doing in my office, or doing in Tijuana, or that Paul is a piece of shit that stole an article on insulin use that I'd written and emailed to him when I was 17yrs old. lol.
... never returned to Mexico after that.