There is an interaction between SSRIs and Nolvadex. Supposedly SSRIs makes nolva less effective.
Ive ben on Zoloft for more than a decade and nolva always worked fine for me, always made the gyno symptoms disapear when i took it.
Idk about the Adex/nolva interaction, those studies have been conducted on females, males react differently to AIs..
Anyway nolva is so outdated, when you can have access to newer generation serms and AIs.