never been drunk in your life = never been popular and had very few friends if any at all that is not the least bit debatable, people socialize with alcohol right or wrong that is reality, you not drinking makes you an outcast and oddball
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Non-drinker here with plenty of friends. I didn't drink in college and I actually was worried that I was going to have to pick up a casual habit when I entered the workforce. At various points in my career, my job has had a heavy socializing component.
Drinkers tend to get soooo defensive when you say you don't drink. Its like they assume you're passing judgement on them and they go into analyzing your psychological problems ... which range from fear of losing control, parental attachment issues, lack of proper socialization, mentally abusive in relationships, etc.

After years of turning down drinks at meetings, social functions, blah blah blah, the excuse I've found that elicits the least reaction is something like "I'm sticking to non-alcoholic. Just trying to stay in shape." People just tend to accept it. The funny thing tho is that if you use that excuse at some office birthday cake party, then no one accepts it. Everyone is like "Oh, you like fine. Just have one slice." In that situation, you're actually better off just saying "Naw, I don't eat cake," or whatever it is.