Brock could easily take down Tyson
Tyson is smaller than Overeem and without Overeems training.
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I'm not sure how that isn't obvious to more people on here.
With some serious time in a wrestling training camp, focusing primarily on take-down defense, Mike could possibly keep a fight standing for a few minutes with Brock. I have no idea how he'd be able to do that without such training experience though.
In my mind, the only question is: does Brock have the jaw/chin to take a few strikes from Tyson before inevitably taking Tyson down and controlling him / ground and pounding him before the referee stops the fight?
I would say yes.
Brock proved his ability to take a punch in the Shane Carwin fight where he ate something like 63 punches to the head/face from Carwin in the first round, causing Carwin to get lactic acidosis, and making Lesnar the first fighter to take Carwin into the second round.
I also think the Overeem fight proved that Lesnar had an incredible chin on him. Overeem fed him some massive shots, and he did not knock Lesnar out. In fact, no one in the UFC knocked Lesnar out, and he did fight the very best - these fights make me feel that Lesnar could absorb a few punches from Tyson, until he takes him down and controls him.
There is always the possibility that Tyson is fast enough to hit Lesnar with a flurry of strikes so fast that he can't tell up from down, and ends up knocking him out very quickly.
These are basically two elite super-athletes.
I would almost always go with an MMA fighter over a boxer, especially an elite heavyweight UFC fighter. But Tyson is no regular boxer.
I imagine there are a few simulations of a Lesnar vs. Tyson fight from video games uploaded to YouTube, lol.