Store your ammo in a safe.
Lock your unloaded gun in your car trunk for easy access.
If you need to use your gun (a psychotic killer breaking into your house at 3AM for example), open your safe, get the ammo, go out to your car and get the gun out of the trunk and load it.
Be sure you're not in any of the numerous gun-free zones in your community before shooting.
Observe proper gun handling at all times.