In an MMA cage, probably.
In a street/bar/etc. fight, Tyson would have this fool eating such a whirlwind flurry of punches, each launched with such ferocity, precision and aggression, he wouldn’t know which way was up.
If he managed to duck down in an attempt to take Iron Mike down, the crushing smashes to the back of his head, shoulders and back would quite possibly paralyze him.
Mike was too aggressive, powerful and quick. Too big.