My urologist retired a year ago and I was sent to a new Endo who took me off injections and put me on new nasel gel, The reasoning was I had a blood clot last year and they found my heart was enlarged, and he felt this was a healthier option although I was a TRT patient for over six years. I do feel a little bit better and I lost over 25 pounds but I feel that because I’ve been doing cardio five days a week since my health scare, however my libido is shot to shit and sometimes I feel like shit, I have argued with him numerous times to put me back on injections but he will not budge., I don’t know if it’s Mira actually misses the injections or it is my old inner bodybuilder idiot mindset that misses it? Should I switch to a new Endo or just accept it?
Assuming this post by the OP isn't pure spam or a scam, the method of administration for testosterone should NOT impact the probability of developing clots.
To be fair, the studies on whether Testosterone therapy can result with the development of blood clots is inconclusive. Some studies suggest a correlation, while others do not find a significant association. Although the FDA warns about the potential risk of blood clots with testosterone products, I would take that with a grain of salt, as nothing the FDA suggests impresses me much. What I've read over the years suggests that Testosterone use can augment the activation of the coagulation system (via the Tissue Factor system - a protein within cells that initiates the clotting process through the formation of thrombin). However, it remains unclear whether this correlation definitively implies causation, given that a lot more factors should be taken into consideration when considering who will develop a clot versus who won't while on Testosterone therapy (i.e. some people can use steroids all of their lives and never get a blood clot, others can use steroids for 6 months and die of a heart attack caused by a clot that traveled to their heart).
Ultimately, what causes someone to develop clots when on Testosterone therapy is the systemic impact of the hormone, creating a hypercoagulable state. The method of administration, such as injections versus gel, is unlikely to be a determining factor. Although I could be mistaken (I don't use Testosterone), it seems improbable that the method of administration would influence systemic adverse effects.
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