Author Topic: off the meds  (Read 17462 times)

Van_Bilderass

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Re: off the meds
« Reply #150 on: December 18, 2023, 11:29:50 PM »
It's a strong drug, it will likely stabilise things. All the best, sincerely.

Although venlafaxine is my base drug, early on I requested the addition of mirtazapine. The combo was called "California rocket fuel" and for a couple of decades it was the go-to for the most severe cases of depression. I don't know lately, if it has been surpassed. I know there are lists of the most effective drugs for depression and anxiety, based on statistics. I was also given Wellbutrin the past couple of years but I don't always take the mirta and Wellbutrin. The Wellbutrin supposedly addresses dopamine specifically though some experts contest that. They also contest that venlafaxine does much or anything wrt noradrenaline.

Kwon

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Re: off the meds
« Reply #151 on: December 19, 2023, 04:46:47 AM »
JEFFREY

SSRI(selective serotonin reuptake inhibitor)-meds like Citalopram, Sertraline/Zoloft works specifically on the Serotonine-system.

-
SNRI-meds affects several systems.

Duloxetine raises both Dopamine, Noradrenaline and Serotonine-levels.

Venlafaxin (Efexor, Efexor Depot)
Duloxetin (Cymbalta)

Milnacipran (Ixel)



So check with your doc for MILNACIPRAN/IXEL

Q

bhank

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Re: off the meds
« Reply #152 on: December 19, 2023, 04:54:32 AM »
JEFFREY

SSRI(selective serotonin reuptake inhibitor)-meds like Citalopram, Sertraline/Zoloft works specifically on the Serotonine-system.

-
SNRI-meds affects several systems.

Duloxetine raises both Dopamine, Noradrenaline and Serotonine-levels.

Venlafaxin (Efexor, Efexor Depot)
Duloxetin (Cymbalta)

Milnacipran (Ixel)



So check with your doc for MILNACIPRAN/IXEL

Or just plan a fucking vacation at a tropical paradise. I would be depressed as well if I hadn't had one in 5 years. Anyone who picks an SSRI without first trying a nice vacation is a fucking jackass.

falco

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Re: off the meds
« Reply #153 on: December 19, 2023, 05:00:37 AM »
Or just plan a fucking vacation at a tropical paradise. I would be depressed as well if I hadn't had one in 5 years. Anyone who picks an SSRI without first trying a nice vacation is a fucking jackass.

Have to agree with bhanky here. Something about looking at gals in bikini's all day is healing.

Kwon

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Re: off the meds
« Reply #154 on: December 19, 2023, 05:04:35 AM »
Have to agree with bhanky here. Something about looking at gals in bikini's all day is healing.

Jeff has a woman, he is married right?

Q

JackTheRipper

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Re: off the meds
« Reply #155 on: December 19, 2023, 05:06:34 AM »
Not going too well at the moment
If I could explain how my head is at the moment its this


Cant focus on anything, keep telling myself to shut the fuck up even though Im not talking

Depresssion is a twat
always knew you were a fucking weirdo

joswift

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Re: off the meds
« Reply #156 on: December 19, 2023, 05:52:05 AM »
Or just plan a fucking vacation at a tropical paradise. I would be depressed as well if I hadn't had one in 5 years. Anyone who picks an SSRI without first trying a nice vacation is a fucking jackass.

apart from a weekend in Vegas you haven't been anywhere else since you have been posting here

I bet you cant leave the country.

bhank

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Re: off the meds
« Reply #157 on: December 19, 2023, 05:56:08 AM »
apart from a weekend in Vegas you haven't been anywhere else since you have been posting here

I bet you cant leave the country.


Correct my passport is expired. I need to get the phoitos taken my wife already filled out my application paperwork. I like to take my vacations to snowboard in the winter. I have gone snowboarding every year. I live at the beach all summer. And regardless I am not the one complaining about depression. If I was depressed I would book a trip somewhere and try a vacation to cheer myself up before spending the same money to talk to someone about why I am sad and taking nasty fucking drugs. I mean what do you have to lose? Book a vacation it will cheer you up doesn't have to be a beach go climb a mountain buy a motorcycle and take a tour whatever floats your boat.

The point is you change your situation if you are unhappy with it. You don't take something to change your perspective of it.

joswift

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Re: off the meds
« Reply #158 on: December 19, 2023, 06:03:23 AM »
Correct my passport is expired. I need to get the phoitos taken my wife already filled out my application paperwork. I like to take my vacations to snowboard in the winter. I have gone snowboarding every year. I live at the beach all summer. And regardless I am not the one complaining about depression. If I was depressed I would book a trip somewhere and try a vacation to cheer myself up before spending the same money to talk to someone about why I am sad and taking nasty fucking drugs. I mean what do you have to lose? Book a vacation it will cheer you up doesn't have to be a beach go climb a mountain buy a motorcycle and take a tour whatever floats your boat.

The point is you change your situation if you are unhappy with it. You don't take something to change your perspective of it.

Amazing, from insulting me yesterday to coming across all positve
Exactly there is nothing wrong with you. You don't have any kind of disease. Your life just sucks and you are too much of a pussy to fix it. So you get medicated by Drs and talk about how to accept your shit life and cry about your disease instead of changing it. Pussy go ahead kill yourself I will piss on your grave or be a godamn man rub some fucking dirt on it and go make a better life maybe start with a vacation
Tell Brian I said hello,



If anyone needed proof Brian isnt the only one on the account read the above post

bhank

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Re: off the meds
« Reply #159 on: December 19, 2023, 06:09:40 AM »
Amazing, from insulting me yesterday to coming across all positveTell Brian I said hello,



If anyone needed proof Brian isnt the only one on the account read the above post

Who is being positive you are still a fucking Cunt

OneMoreRep

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Re: off the meds
« Reply #160 on: December 19, 2023, 06:17:08 AM »
What I'll add is that antidepressant medications don't work for everyone and MAYBE there is reason why they just haven't been as effective for you.

There's a large scale clinical study that was conducted years ago (STAR*D) which showed that the response rate for antidepressants (types that directly affect Serotonin availability) for patients that had not been treated with antidepressants before was around 50%. You could be one of the individuals who just doesn't have a good response to SSRI's or SNRI's.

Why does this happen?

Research has shown that there is a genetic variation that some individuals have that makes them impervious to the effects of the various medications that increase the availability of Serotonin (SSRIs and SNRIs etc.). These patients carry a defective component to a gene which allows for more versus less serotonin transporters to be available, which in turn leads to less active sites for Serotonin Reuptake Inhibitors (these drugs actually bind to Serotonin transporters), which reduces the response to these medications. This shit probably makes little sense to most people, but I think a picture can illustrate this detail a lot more:



You could be one of those individuals that have a shorter allele resulting in lower transcription rates. Your provider can determine this with genetic testing, which would reduce the amount of time possibly wasted in trying to figure out what medications you might actually respond to.

"1"

bhank

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Re: off the meds
« Reply #161 on: December 19, 2023, 06:28:54 AM »
What I'll add is that antidepressant medications don't work for everyone and MAYBE there is reason why they just haven't been as effective for you.

There's a large scale clinical study that was conducted years ago (STAR*D) which showed that the response rate for antidepressants (types that directly affect Serotonin availability) for patients that had not been treated with antidepressants before was around 50%. You could be one of the individuals who just doesn't have a good response to SSRI's or SNRI's.

Why does this happen?

Research has shown that there is a genetic variation that some individuals have that makes them impervious to the effects of the various medications that increase the availability of Serotonin (SSRIs and SNRIs etc.). These patients carry a defective component to a gene which allows for more versus less serotonin transporters to be available, which in turn leads to less active sites for Serotonin Reuptake Inhibitors (these drugs actually bind to Serotonin transporters), which reduces the response to these medications. This shit probably makes little sense to most people, but I think a picture can illustrate this detail a lot more:



You could be one of those individuals that have a shorter allele resulting in lower transcription rates. Your provider can determine this with genetic testing, which would reduce the amount of time possibly wasted in trying to figure out what medications you might actually respond to.

"1"

Exercise increases Serotonin this is just further proof Jeff doesn't even lift. If you are unhappy fix what you are unhappy about everything is not a genetic chemical imbalance out of your control exercise, travel, diet, even socializing with other people and animals changes your godamn brain chemistry, you don't need weird nasty drugs.

Try gardening when I was growing in Maui I noticed a real difference

https://www.gardeningknowhow.com/garden-how-to/soil-fertilizers/antidepressant-microbes-soil.htm

Whatever you do and I can not emphasize this enough do not stand next to bhank and certainly do not let anyone get a photo of you standing next to bhank. It would absolutely crush your fragile mind to see how badly he dwarves you.

Raymondo

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Re: off the meds
« Reply #162 on: December 19, 2023, 06:36:50 AM »
Amazing, from insulting me yesterday to coming across all positveTell Brian I said hello,



If anyone needed proof Brian isnt the only one on the account read the above post

Likely he sobered up, the poor guy spends a considerable portion of the day high as a kite.

joswift

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Re: off the meds
« Reply #163 on: December 19, 2023, 07:13:46 AM »
Exercise increases Serotonin this is just further proof Jeff doesn't even lift. If you are unhappy fix what you are unhappy about everything is not a genetic chemical imbalance out of your control exercise, travel, diet, even socializing with other people and animals changes your godamn brain chemistry, you don't need weird nasty drugs.

Try gardening when I was growing in Maui I noticed a real difference

https://www.gardeningknowhow.com/garden-how-to/soil-fertilizers/antidepressant-microbes-soil.htm

Whatever you do and I can not emphasize this enough do not stand next to bhank and certainly do not let anyone get a photo of you standing next to bhank. It would absolutely crush your fragile mind to see how badly he dwarves you.
Are you talking about Brian or are you talking in the third person?


 

falco

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Re: off the meds
« Reply #164 on: December 19, 2023, 07:29:59 AM »
Have to agree with bhanky GIMMICK here. Something about looking at gals in bikini's all day is healing.

Fixed.

Kwon

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Re: off the meds
« Reply #165 on: December 19, 2023, 09:03:18 AM »
Jeffrey has a wife so should not look at girls in bikini


Also, he doesn't need to travel abroad, everything is in the UK

If you want to visit India, just travel to Birmingham.
Q

bhank

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Re: off the meds
« Reply #166 on: December 19, 2023, 09:08:44 AM »
Likely he sobered up, the poor guy spends a considerable portion of the day high as a kite.

I do not like feeling ill. I have a sensitive stomach. I do not use intoxicants. I don't like them. I use a Delta 8 cannabis vape. It is a milder form of THC than Delta 9 thc for my appetite and nausea because of my stomach and digestive issues that is it. I do not take any of my multiple prescribed medications for Crohn's. I use delta 8 only.  It does not get you high as a kite lol.

I would actually recommend Jeff try cannabis over pills
 

bhank

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Re: off the meds
« Reply #167 on: December 19, 2023, 09:10:23 AM »
Jeffrey has a wife so should not look at girls in bikini


Also, he doesn't need to travel abroad, everything is in the UK

If you want to visit India, just travel to Birmingham.


The UK has a reputation for being cold rainy and dreary

Raymondo

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Re: off the meds
« Reply #168 on: December 19, 2023, 09:54:34 AM »
I do not like feeling ill. I have a sensitive stomach. I do not use intoxicants. I don't like them. I use a Delta 8 cannabis vape. It is a milder form of THC than Delta 9 thc for my appetite and nausea because of my stomach and digestive issues that is it. I do not take any of my multiple prescribed medications for Crohn's. I use delta 8 only.  It does not get you high as a kite lol.

I would actually recommend Jeff try cannabis over pills

That's like saying beer will not get you as drunk as wine because it has lower alcohol content. But if you have 20 beers...

Brian "I don't get high" Hankins


wes

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Re: off the meds
« Reply #169 on: December 19, 2023, 10:12:32 AM »
That's like saying beer will not get you as drunk as wine because it has lower alcohol content. But if you have 20 beers...

Brian "I don't get high" Hankins


Stoned To The Bone!  LOL   ;D

GymnJuice

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Re: off the meds
« Reply #170 on: December 19, 2023, 11:01:23 AM »
Jeffrey has a wife so should not look at girls in bikini


Also, he doesn't need to travel abroad, everything is in the UK

If you want to visit India, just travel to Birmingham.


Can you reach Dubai via Birmingham?

Kwon

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Re: off the meds
« Reply #171 on: December 19, 2023, 11:36:43 AM »
Can you reach Dubai via Birmingham?

The main Arab Muslim communities in the UK live in the Greater London area, with smaller numbers living in Manchester, Liverpool, and Birmingham.

There are also sizable and long-established Yemeni Arab communities living in both Cardiff and the South Shields area near Newcastle-upon-Tyne.
Q

bhank

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Re: off the meds
« Reply #172 on: December 19, 2023, 02:30:31 PM »
That's like saying beer will not get you as drunk as wine because it has lower alcohol content. But if you have 20 beers...

Brian "I don't get high" Hankins



That is literally 2 minutes after I rolled out of bed in the morning it’s the morning ab check before coffee or a shower

bhank

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Re: off the meds
« Reply #173 on: December 19, 2023, 02:39:07 PM »
That's like saying beer will not get you as drunk as wine because it has lower alcohol content. But if you have 20 beers...

Brian "I don't get high" Hankins



I could smoke cannabis all day instead of breathing air and still pass a sobriety test it is not an intoxicant to a regular user. You can still go to the gym drive a car climb a mountain take a math test whatever it is not powuonnit does not inebriate and incapacitate you

Cannabis gets a regular user about as high as a cigarette gets a regular smoker or a cup of coffee does to a coffee drinker and I prefer delta 8 as it is milder I use it for my stomach and digestion and appetite not to be inebriated I don’t like feeling sleepy

deadz

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Re: off the meds
« Reply #174 on: December 19, 2023, 02:46:13 PM »
That's like saying beer will not get you as drunk as wine because it has lower alcohol content. But if you have 20 beers...

Brian "I don't get high" Hankins


12" neck. Not aging well.
T