Sort of, yes, equipoise, but F450 is on track. 1.5 a day is therapeutic for most users and more get's the job done even better. Bear in mind this is the 'flush' naicin (also called nicotinic acid) and not niacinamide or nicotinamide which are also B3s but will not work in this role. Also note that niacin will reduce LDL cholesterol (including VLDL - which most statins will not do) and also reduce triglycerides while increasing HDL cholesterol. As f450 points out, Big Pharma would dearly love to outlaw the OTC sale of niacin as it gets an excellent result with problematic blood lipids/cholesterol without affecting the production of CoQ10 in the liver - the number 1 mitochondrial fuel. The pharmaceutical industry have succeeded in some nanny states around the world and they won't stop coercing and bribing until they get their way - with this and a basket of other herbals, vitamins and trace elements.
New users should start with 100mg with or immediately after meals three times a day and work up 100g every week thereafter. You're "in the zone" from 500mg 3 x a day for picking up noticeable changes in blood tests after 3-4 weeks. More will give even further gratification. Good luck.
