Not read the thread, but Lyle is a geek.
His theory doesn't explain the jacked natty calisthenics guys all across the world.
Volume, frequency and intensity all play roles in natty gains, but frequency and volume trump progressive overload imo (because strength has factors besides muscle).
All the over analysing science BS is a hindrance. Back in the day you'd watch pumping iron, learn from practical experience in the gym and then get your first cycle of dbol from the gym dealer.
x2
These are the facts in my opinion:
(1) Volume is king if your goal is size/mass, and it's a lot easier to increase volume when working with light/moderate weights than with heavy weights.
(2) If you want to get appreciably stronger in a particular rep range then you need to train in that rep range, don't expect something like GVT or 20-rep squats to up your one-rep max all that much.
I'm very confident in #1 and moderately confident in #2
Most people want to be big but also want to throw around big weights; hard to make progress on either goal trying to do both of these things.
By "volume" I mean weight x reps x sets