Peptides/ GH

[beakdoctor]

So many new GH peptides hard to keep up with what does what, especially with the craze on all the fat loss peptides.

I used a GH secretagogue about 7 or 8 years ago and it quickly healed 2 old nagging injuries. Also caused me to eat like a fucking pig, retain water and BP was sky high.

The one currently getting the most talk seems to be semorelin (sp?)

Any knowledgeable getbiggers have an opinion on what's best for muscle growth for the 50 year old + bodybuilder/weight lifter? Which one is best for injury/repair? (Aside from BPC and TB, which are already well known and documented)

[Grape Ape]

https://www.getbig.com/boards/index.php?topic=700609.0

[beakdoctor]

https://www.getbig.com/boards/index.php?topic=700609.0

Have not clicked on link.

I'm going to say its a link to Hankins delusional plot to start selling peptides.

I will now click on link.

Survey says?

[Grape Ape]

If you don't trust the link, just find it stickied on the nutrition board.

[beakdoctor]

Have not clicked on link.

I'm going to say its a link to Hankins delusional plot to start selling peptides.

I will now click on link.

Survey says?

Thanks for the link.

Great thread. Good information. Dealing with a tricep injury right now. Thought it was torn but after MRI, Ortho doesn't seem to think its a tear. Not really sure what the deal is. Could be a tear that was missed by ortho, could be some kind of nerve damage. FWIW I suffered no bruising and very little pain. In fact it took quite a while for me to even realize the muscle was damaged. It seems to be slightly improving but it has been months. The more rest I give it, the more it seems to heal. But so little 'improvement' it could just be wishful thinking on my part. Ortho is stumped so he's referring me to a specialist. I'll see what the specialist says and if he's lost too, I guess ill try bpc, tb or one of the other promising peptides.

Mods feel free to delete or merge with Grapes link.

[Van_Bilderass]

I think the Ipamorelin plus CJC-1295 combo is the most popular and touted as the most potent GH releasing combo. If I'm not mistaken the Ipamorelin doesn't affect ghrelin and cortisol and some other hormones so you don't get the appetite increase.

Especially, if I thought the healing peptides had possibly injection site preferential effect I would definitely add IGF-1 DES or IGF-1LR3 or both to the "Wolverine stack" of BPC and TB. Probably a tiny dose of Fiasp insulin too to further agonize IGF receptors. Ah hell, throw the copper peptide in there too. I mean if I had the money and recovery was very important to me. It's a bit of witchcrafting because you won't find studies on a combo such as this any time soon but individually these seem probably fairly safe.

For nerve damage recovery GH does theoretically make a lot of sense to try, which is why I mentioned the IGF-1 derivatives.

[joswift]

peptides

Fucking lol...

[beakdoctor]

peptides

Fucking lol...

I think guys like Leo Longevity, that Dr. Tony asshole, Bostin Lloyd etc give them a bad name. There's a lot of evidence supporting their recuperative/healing properties and use for treating injuries.

[joswift]

I think guys like Leo Longevity, that Dr. Tony asshole, Bostin Lloyd etc give them a bad name. There's a lot of evidence supporting their recuperative/healing properties and use for treating injuries.

Injecting yourself multiple times a day/week with what is in most cases fucking sterile water

A total scam

[JK]

A few years ago, I used a combination of Ipamorelin and CJC-1295, which cured my shoulder injury. Now I use GH.

[beakdoctor]

A few years ago, I used a combination of Ipamorelin and CJC-1295, which cured my shoulder injury. Now I use GH.

What was the injury? Tear in rotator cuff?

[JK]

What was the injury? Tear in rotator cuff?

Honestly, I don't know; I've never been to a doctor about it. It wasn't severe pain, and I could train with it, but I felt discomfort during overhead presses and bench presses.

[Methyl m1ke]

Insofar as I know there aren't really any peptides worth taking. Use GH if you want it's effects.

[Griffith]

Insofar as I know there aren't really any peptides worth taking. Use GH if you want it's effects.

MK-677 works, several of us have used it for some time and posted about it.

[nobody in particular]

i'm  currently recovering from shoulder reco surgery. had some very frank discussions with surgeons prior.interestingly one was 100% clear about NOT using GH in the first month or two. WEnt to the point of saying there is research that it interferes with tendons and ligaments healing early on.

I don't know the underlying mechanism,, but I'm going to wildly speculate (and may bde way way off here) that gh interferes with insulin sensitivity and as we know insulin dependant diabetics can get fucking big but threy don't heal well from cuts and the like.

so I'm using bpc157 and tb500 and currently 400mg per week of test e and 200mg of eq. I'd played around with those two before surgery and that ratio left  my estrogen in a good range, so I'm sticking with it, was probably going to go higher overall but at this stage can't really see a reason to.

Anyone with more knowledge on possible reasons why gh wouldn't be great immediately post surgery ( amd to be clear in all cases on my shoulder the tendon/ligament snapped mid way, nmone of them ripped out at the bone insertion taking a piece of bone with the,m (the more ideal of tears as far as surgery and overall post surgical return to max abilitities go)

[ProudVirgin69]

i'm  currently recovering from shoulder reco surgery. had some very frank discussions with surgeons prior.interestingly one was 100% clear about NOT using GH in the first month or two. WEnt to the point of saying there is research that it interferes with tendons and ligaments healing early on.

I don't know the underlying mechanism,, but I'm going to wildly speculate (and may bde way way off here) that gh interferes with insulin sensitivity and as we know insulin dependant diabetics can get fucking big but threy don't heal well from cuts and the like.

so I'm using bpc157 and tb500 and currently 400mg per week of test e and 200mg of eq. I'd played around with those two before surgery and that ratio left  my estrogen in a good range, so I'm sticking with it, was probably going to go higher overall but at this stage can't really see a reason to.

Anyone with more knowledge on possible reasons why gh wouldn't be great immediately post surgery ( amd to be clear in all cases on my shoulder the tendon/ligament snapped mid way, nmone of them ripped out at the bone insertion taking a piece of bone with the,m (the more ideal of tears as far as surgery and overall post surgical return to max abilitities go)

GH 100% induces insulin resistance.  Granted, the dosages involved with healing (ie: small) are unlikely to cause significant resistance, but it is a known side effect.

With regards to it interfering with healing, no clue.  If you’re in contact with the surgeon ask them if they would be so kind as to provide you with the literature making such claims for the sake of your curiosity.  I wouldn’t be surprised, if it was some kind of miracle healing agent we’d see more use of it in an off-label manner by ortho surgeons.  As far as I know, none of them do. 

[Krankenstein]

Insofar as I know there aren't really any peptides worth taking. Use GH if you want it's effects.

Like helping someone look better on stage the day before a bodybuilding show?

[Krankenstein]

i'm  currently recovering from shoulder reco surgery. had some very frank discussions with surgeons prior.interestingly one was 100% clear about NOT using GH in the first month or two. WEnt to the point of saying there is research that it interferes with tendons and ligaments healing early on.

I don't know the underlying mechanism,, but I'm going to wildly speculate (and may bde way way off here) that gh interferes with insulin sensitivity and as we know insulin dependant diabetics can get fucking big but threy don't heal well from cuts and the like.

so I'm using bpc157 and tb500 and currently 400mg per week of test e and 200mg of eq. I'd played around with those two before surgery and that ratio left  my estrogen in a good range, so I'm sticking with it, was probably going to go higher overall but at this stage can't really see a reason to.

Anyone with more knowledge on possible reasons why gh wouldn't be great immediately post surgery ( amd to be clear in all cases on my shoulder the tendon/ligament snapped mid way, nmone of them ripped out at the bone insertion taking a piece of bone with the,m (the more ideal of tears as far as surgery and overall post surgical return to max abilitities go)

2018 - Effect of recombinant human growth hormone on rotator cuff healing after arthroscopic repair: preliminary result of a multicenter, prospective, randomized, open-label blinded end point clinical exploratory trial
https://pubmed.ncbi.nlm.nih.gov/29337026/

2013 - Human growth hormone may be detrimental when used to accelerate recovery from acute tendon-bone interface injuries
https://pubmed.ncbi.nlm.nih.gov/23636184/

In as far as I can see (from reading into this) is that 4 - 6 weeks post surgery HGH is no bueno.  After that when you get farther into the rehab, it would be much more beneficial.

The wound healing problems come more from chronic high blood sugar levels which results in poor circulation (especially in the small capillaries which are near the skin) and nerve damage. 

One thing to consider is the effect of test on tendons.  There is the thought that the effect of test on the muscle more so than the tendon leads to injury, but then there is some research on the improvement of collagen in a tendon causing it to become stronger.  Both times I had surgery on my shoulder (rotator repair and then bicep repair) I was asked if I used test.  The surgeries were 8 years apart so it seems its a common thing.

I do know it takes a lot more force to produce an avulsion fraction (tendon pulled from insertion) than a partial (or full) thickness tear.  Maybe the avulsion is better due to how fast bone healing occurs but I would imagine there is still more for the surgeon to do with it.