answer to question in regards to sustanon

[bigkahuna]

gh15 what is your opinion on t bol?

and if one is prone to acne would test e be superior to sust in this regard?

[biceps]

Potential of testosterone buciclate for male contraception: endocrine differences between responders and nonresponders

HM Behre, S Baus, S Kliesch, C Keck, M Simoni and E Nieschlag
Institute of Reproductive Medicine of the University (WHO Collaborating Center for Research in Human Reproduction), Munster, Germany.

Suppression of serum LH and FSH, by testosterone (T) alone or in combination with other agents, has proved to be the most promising approach to male contraception. T enanthate, the only androgen preparation tested in male contraceptive efficacy trials so far, must be injected every week due to its short terminal elimination half-life of 4.5 days and leads to supraphysiological T serum levels. A new T ester synthesized under WHO and NIH auspices, testosterone buciclate (TB), showed a favorable pharmacokinetic profile, with a terminal half- life of 29.5 days when tested in hypogonadal men. Here we describe the results of the first clinical trial with TB for male contraception. After two control examinations, normal healthy male volunteers were given a single im injection of 600 mg TB (group I; n = 4) and 1200 mg TB (group II; n = on day 0. Follow-up examinations were performed every 2 weeks up to week 32. In both groups mean serum T levels remained in the normal physiological range throughout the study course. Serum levels of dihydrotestosterone (DHT) showed a dose- and time- dependent increase, with serum levels slightly above the normal range in group II for several weeks and a maximal concentration of 3.8 +/- 0.5 nmol/L (mean +/- SE) in week 6. No suppression of spermatogenesis to oligozoospermia was observed in group I. However, in group II, spermatogenesis was suppressed to azoospermia in three of eight volunteers in week 10 that persisted up to weeks 14, 20, and 22, respectively. In these three men, LH and FSH were suppressed by TB injections to the respective assay detection limits, whereas in the other five subjects, mean serum levels were only decreased to values near the lower normal limit for LH and FSH, respectively. In addition, throughout the study course, a significant difference in serum sex hormone-binding globulin was detected between the responders (mean values, 21.2-26.4 nmol/L) and nonresponders (mean values, 36.2-46.3 nmol/L). Serum levels of LH as well as total and free T at baseline and after TB injection were lower in the responders than in the nonresponders. Both subgroups showed similar increases in serum LH and FSH after GnRH stimulation. In a newly introduced GnRH antagonist suppression test, serum LH and T were decreased to significantly lower levels in the responders. These results indicate a different hormonal equilibrium and probably different susceptibility to feedback regulation of the responders compared to the nonresponders.

Thanks, 

[biceps]

Buciclate and Undecanoate (Nebido): pretty much useless for bodybuilding purposes. If a bodybuilder went to jail for a few months it might have some utility. 

I am not planing to used for any purpose, I had sum information on the preclinical studies in 1989 on castrated rhesus monkeys and the 2 scientist Rajalkshmi and Ramakrishan, were talking about favorable results. I never head chance to see the final results. Is was just  curios.

[bigbobs]

And what else, Bigbobs?  4 amps of test and what else?   

I meant a total of about 1000 to 1200 mg including all drugs combined.

I guess it's largely genetic.  I'm sure if Ronnie or Huge Nasser only take 3-4 amps a week of test they would still be able to compete at 220ish right?

[bigbobs]

GH15 when you say that to compete at 250+ you need 2 amps of Sustanon per day is that stacking with other stuff like dbol, deca, etc. or just taking test alone?

[trab]

Post the specific reference. All data I've seen shows that IM testosterone esters like Enanthate peak at around 24-48h.

Edit, this is what the blood levels look like after a single injection so it basically peaks after a day

Yes but thats only ONE SHOT!

You fail to recognize build up to higher steady state plasma level.

All these dumb ass here propose 1amp sus ew = waste of drug and knock down Nat Test for no reason.

Experienced user gonna fill 3-4cc to start off a SUS only kick off.

If you shoot 10cc of SUS in a couple days -- 10 x 30 Tprop = 300Tp
                                                            10 x 60 Tpheny = 600Tpy
                                                             10 x 60 Tiso     = 600Ti
                                                              10 x 100 Tdeca = 1000TD

ANy man that tollerates Testo decently and Tprop in particular could handle that.
You'd be riding 1000mg of Td max towards day 10-14. The rest have mostly decayed.

If you understand how this drug released and decays you can avoid a lot of shots and not ride a roller coaster.
But most "SUS" is fake stateside.

2-3cc of SUS every 17th day is a great HRT dose.
Experienced user wants beef? Fill 'er UP!
If too stupid to count to 21, dont use sustanon. That rules out plenty guys here.

[Van_Bilderass]

Yes but thats only ONE SHOT!

You fail to recognize build up to higher steady state plasma level.

Yes I understand. I was just showing when the test peaks after that one injection. That's not the absolute peak after shooting it regularly for a while obviously.