Author Topic: MESSAGE TO EPHEDRINE USERS!!!!!!!  (Read 30720 times)

Necrosis

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Re: MESSAGE TO EPHEDRINE USERS!!!!!!!
« Reply #100 on: April 04, 2008, 07:44:53 PM »
Please elaborate. What kind of negative effects could expect from chronic ephedrine use? How would the side effects manifest? One negative effect I think is fairly common with long term use is BPH.

Aspirin is bad on the stomach. Doing 300mg of aspirin a few times a day, or whatever some recommend, for an extended period could be downright dangerous. One baby aspirin a day, maybe not too bad.

81mg of aspirin has shown prophylactic effects against various cancers, and cardiovascular disease, many healthy people should take it. It has also shown effects against dementia and alzhemiers by reducing tau tangles, plauqes etc..

for one you can permently screw up your adrenal fucntion. exogenous application of eppies causes the adrenals to pump out more catecholamines, chronic use can cause damage. Also, eph is not selective in its beta agonism, thus you get the goodies, the fat loss with the bad stuff, such as increased heart rate, ateriole constriction, higher blood pressure all of this has a cumulative effect. the short burst of catecholamines is also bad for the psyche when coming down, similar to amphetamines.

beta receptor downregulation could occur, Hence the need for higher and higher doses, your body maintains homeostasis above all else, dont think there isnt consequences to those actions. The higher doses cause more cardiovascular issues. Not to mention that catecholamine release will inhibit the parasympathetic system via sympthomimetic action of eph., causing poor digestion among other things.

im not saying dont use it, im saying long term chronic use of any stim is dangerous, especially a shotgun stim like ephedrine.

Van_Bilderass

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Re: MESSAGE TO EPHEDRINE USERS!!!!!!!
« Reply #101 on: April 04, 2008, 07:50:41 PM »
81mg of aspirin has shown prophylactic effects against various cancers, and cardiovascular disease, many healthy people should take it. It has also shown effects against dementia and alzhemiers by reducing tau tangles, plauqes etc..

for one you can permently screw up your adrenal fucntion. exogenous application of eppies causes the adrenals to pump out more catecholamines, chronic use can cause damage. Also, eph is not selective in its beta agonism, thus you get the goodies, the fat loss with the bad stuff, such as increased heart rate, ateriole constriction, higher blood pressure all of this has a cumulative effect. the short burst of catecholamines is also bad for the psyche when coming down, similar to amphetamines.

beta receptor downregulation could occur, Hence the need for higher and higher doses, your body maintains homeostasis above all else, dont think there isnt consequences to those actions. The higher doses cause more cardiovascular issues. Not to mention that catecholamine release will inhibit the parasympathetic system via sympthomimetic action of eph., causing poor digestion among other things.

im not saying dont use it, im saying long term chronic use of any stim is dangerous, especially a shotgun stim like ephedrine.

I have seen some differing opinions on the aspirin as preventative medicine. There was some issue with people having heart attacks when dropping it cold turkey. Then there were some issue with potential kidney and liver toxicity with long term use. I think it's like with everything, there are some good effects along with some potentially bad. Who do you think should take a baby aspirin daily?

Do you know of any research showing adrenal damage from ephedrine or other stimulants?

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Re: MESSAGE TO EPHEDRINE USERS!!!!!!!
« Reply #102 on: April 04, 2008, 07:51:27 PM »
100mg a day for more than a week?  ;D With espresso shots, instant coffee, caffine tabs from cvs, and diet soda?

When I stick to 25 mg a day or slightly more, I don't have any negative side effects expect for some insomnia; positives include getting wired.  ;D

Maybe different people respond differently. 240 said his heart felt weird while taking ephedrine, and mine does with very high doses(100mg) for more than a week or so.
no, but 100 mg at ONE TIME, along with i dont know how many redlines, endless blunts, a tab of x.



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Re: MESSAGE TO EPHEDRINE USERS!!!!!!!
« Reply #103 on: April 04, 2008, 07:56:29 PM »
A

Necrosis

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Re: MESSAGE TO EPHEDRINE USERS!!!!!!!
« Reply #104 on: April 04, 2008, 07:57:22 PM »
I have seen some differing opinions on the aspirin as preventative medicine. There was some issue with people having heart attacks when dropping it cold turkey. Then there were some issue with potential kidney and liver toxicity with long term use. I think it's like with everything, there are some good effects along with some potentially bad. Who do you think should take a baby aspirin daily?

Do you know of any research showing adrenal damage from ephedrine or other stimulants?

ill respond to your post tom as im going to bed, just so you know that i will respond. Ill post some stuff from pubmed tom.

imo all healthy adults should take baby aspirin. liver toxicity is minimal at that dosage nothing as is kidney. reduced blood pressure from blood thinning would offset that effect. Intestinal ulceration is the main issue, but 81 is a minimal amount of ASA. preventing heart attack, the number one killer, various forms of cancer, and biomarkers of metabolic syndrome far outweigh the risks in my opinion.

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Re: MESSAGE TO EPHEDRINE USERS!!!!!!!
« Reply #105 on: April 04, 2008, 07:59:18 PM »
25mg? thats it?  ???

http://wilstar.com/caffeine.htm
no, 25mg of ephedrine, not 25mg caffiene...thats like 1/2 of a diet soda

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Re: MESSAGE TO EPHEDRINE USERS!!!!!!!
« Reply #106 on: April 04, 2008, 08:18:58 PM »
no, 25mg of ephedrine, not 25mg caffiene...thats like 1/2 of a diet soda
oh my bad.
A

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Re: MESSAGE TO EPHEDRINE USERS!!!!!!!
« Reply #107 on: April 04, 2008, 08:40:56 PM »
Adrenal Fatigue is a collection of signs and symptoms, known as a "syndrome", that results when the adrenal glands function below the necessary level. Most commonly associated with intense or prolonged stress, it can also arise during or after acute or chronic infections, especially respiratory infections such as influenza, bronchitis or pneumonia. As the name suggests, its paramount symptom is fatigue that is not relieved by sleep but it is not a readily identifiable entity like measles or a growth on the end of your finger. You may look and act relatively normal with Adrenal Fatigue and may not have any obvious signs of physical illness, yet you live with a general sense of unwellness, tiredness or "gray" feelings. People suffering from Adrenal Fatigue often have to use coffee, colas and other stimulants to get going in the morning and to prop themselves up during the day.

This syndrome has been known by many other names throughout the past century, such as non-Addison's hypoadrenia, sub-clinical hypoadrenia, neurasthenia, adrenal neurasthenia, adrenal apathy and adrenal fatigue. Although it affects millions of people in the U.S. and around the world, conventional medicine does not yet recognize it as a distinct syndrome.

Adrenal Fatigue can wreak havoc with your life. In the more serious cases, the activity of the adrenal glands is so diminished that you may have difficulty getting out of bed for more than a few hours per day. With each increment of reduction in adrenal function, every organ and system in your body is more profoundly affected. Changes occur in your carbohydrate, protein and fat metabolism, fluid and electrolyte balance, heart and cardiovascular system, and even sex drive. Many other alterations take place at the biochemical and cellular levels in response to and to compensate for the decrease in adrenal hormones that occurs with Adrenal Fatigue. Your body does its best to make up for under-functioning adrenal glands, but it does so at a price.


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Re: MESSAGE TO EPHEDRINE USERS!!!!!!!
« Reply #108 on: April 04, 2008, 08:42:22 PM »
Adrenal Fatigue is produced when your adrenal glands cannot adequately meet the demands of stress. The adrenal glands mobilize your body's response to every kind of stress (whether it's physical, emotional or psychological) through hormones that regulate energy production and storage, heart rate, muscle tone, and other processes that enable you to cope with the stress. Whether you have an emotional crisis such as the death of a loved one, a physical crisis such as major surgery, or any type of severe repeated or constant stress in your life, your adrenals have to respond. If they don't, or if their response is inadequate, you will experience some degree of Adrenal Fatigue.

In Adrenal Fatigue your adrenal glands function, but not enough to maintain your normal, healthy homeostasis. Their output of regulatory hormones has been diminished by over-stimulation. This over- stimulation can be caused either by a very intense single stress or by chronic or repeated stresses that have a cumulative effect.

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Re: MESSAGE TO EPHEDRINE USERS!!!!!!!
« Reply #109 on: April 04, 2008, 08:44:40 PM »
Adrenal Fatigue is produced when your adrenal glands cannot adequately meet the demands of stress. The adrenal glands mobilize your body's response to every kind of stress (whether it's physical, emotional or psychological) through hormones that regulate energy production and storage, heart rate, muscle tone, and other processes that enable you to cope with the stress. Whether you have an emotional crisis such as the death of a loved one, a physical crisis such as major surgery, or any type of severe repeated or constant stress in your life, your adrenals have to respond. If they don't, or if their response is inadequate, you will experience some degree of Adrenal Fatigue.

In Adrenal Fatigue your adrenal glands function, but not enough to maintain your normal, healthy homeostasis. Their output of regulatory hormones has been diminished by over-stimulation. This over- stimulation can be caused either by a very intense single stress or by chronic or repeated stresses that have a cumulative effect.

Nice cut and paste douchbag

The Coach

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Re: MESSAGE TO EPHEDRINE USERS!!!!!!!
« Reply #110 on: April 04, 2008, 08:47:47 PM »
Nice cut and paste douchbag

Hey, if they won't believe me in my own words (like in the previous post) might as well do it this way........BTW....fuck you! Come back with a debate or don't get involved, what a fucking child!


You have a problem, PM me or go away, you haven't contributed to shit on here Junior!!

I also posted it this was because the other idiot kept saying I was referring to it as a "disease" even after I told him numerous times it wasn't. I'm sorry, what was your take on this subject???????????????

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Re: MESSAGE TO EPHEDRINE USERS!!!!!!!
« Reply #111 on: April 04, 2008, 08:51:17 PM »
Hey, if they won't believe me in my own words (like in the previous post) might as well do it this way........BTW....fuck you! Come back with a debate or don't get involved, what a fucking child!


You have a problem, PM me or go away, you haven't contributed to shit on here Junior!!

::)

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Re: MESSAGE TO EPHEDRINE USERS!!!!!!!
« Reply #112 on: April 04, 2008, 08:52:13 PM »
Hey, if they won't believe me in my own words (like in the previous post) might as well do it this way........BTW....fuck you! Come back with a debate or don't get involved, what a fucking child!


You have a problem, PM me or go away, you haven't contributed to shit on here Junior!!

Go to hell old man, please retire from getbig for the 10th time and get divorced again; aren't you overdue. Three time loser.

The Coach

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Re: MESSAGE TO EPHEDRINE USERS!!!!!!!
« Reply #113 on: April 04, 2008, 08:53:16 PM »
Go to hell old man, please retire from getbig for the 10th time and get divorced again; aren't you overdue. Three time loser.

Nice contribution loser ::)

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Re: MESSAGE TO EPHEDRINE USERS!!!!!!!
« Reply #114 on: April 04, 2008, 08:58:01 PM »
Nice contribution loser ::)
Loser? Loco that word is owned by you. Loser in bodybuilding, Loser in love, Loser in life. Go kill yourself now.

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Re: MESSAGE TO EPHEDRINE USERS!!!!!!!
« Reply #115 on: April 04, 2008, 08:59:53 PM »
enanthate owns you loco!  >:(

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Re: MESSAGE TO EPHEDRINE USERS!!!!!!!
« Reply #116 on: April 04, 2008, 08:59:58 PM »
Loser? Loco that word is owned by you. Loser in bodybuilding, Loser in love, Loser in life. Go kill yourself now.


Ok son....LOL!

The Coach

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Re: MESSAGE TO EPHEDRINE USERS!!!!!!!
« Reply #117 on: April 04, 2008, 09:01:18 PM »
enanthate owns you loco!  >:(

Yes, I can tell..LOL!

Is past your bedtime, go now....scoot :)

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Re: MESSAGE TO EPHEDRINE USERS!!!!!!!
« Reply #118 on: April 04, 2008, 09:05:37 PM »

Ok son....LOL!
Got any of those pictures you like to post from 20 years ago, o and what about those 400lb bench press claims in high school or was it 500lbs. You are a girl and your wife probably depises you by now. Still posting pics of your kis on the internet, i'm sure he will appreciate that later in life. Another family member that will think you are a shitbag what a surprise.

candidizzle

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Re: MESSAGE TO EPHEDRINE USERS!!!!!!!
« Reply #119 on: April 04, 2008, 09:18:04 PM »
Yes, I can tell..LOL!

Is past your bedtime, go now....scoot :)
oh shi your right i was supposed to be asleep 17 minutes ago! hope i dont get grounded!  :D

Camel Jockey

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Re: MESSAGE TO EPHEDRINE USERS!!!!!!!
« Reply #120 on: April 04, 2008, 10:15:52 PM »
JoeLoco will get more HRT scripts from his friendly doctor in order to engage Enanthator in the cage.

Van_Bilderass

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Re: MESSAGE TO EPHEDRINE USERS!!!!!!!
« Reply #121 on: April 04, 2008, 10:27:20 PM »
Coach, do you have the link to the original article you quoted there?

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Re: MESSAGE TO EPHEDRINE USERS!!!!!!!
« Reply #122 on: April 04, 2008, 11:56:03 PM »
Adrenal Fatigue is a collection of signs and symptoms, known as a "syndrome", that results when the adrenal glands function below the necessary level. Most commonly associated with intense or prolonged stress, it can also arise during or after acute or chronic infections, especially respiratory infections such as influenza, bronchitis or pneumonia. As the name suggests, its paramount symptom is fatigue that is not relieved by sleep but it is not a readily identifiable entity like measles or a growth on the end of your finger. You may look and act relatively normal with Adrenal Fatigue and may not have any obvious signs of physical illness, yet you live with a general sense of unwellness, tiredness or "gray" feelings. People suffering from Adrenal Fatigue often have to use coffee, colas and other stimulants to get going in the morning and to prop themselves up during the day.

This syndrome has been known by many other names throughout the past century, such as non-Addison's hypoadrenia, sub-clinical hypoadrenia, neurasthenia, adrenal neurasthenia, adrenal apathy and adrenal fatigue. Although it affects millions of people in the U.S. and around the world, conventional medicine does not yet recognize it as a distinct syndrome.

Adrenal Fatigue can wreak havoc with your life. In the more serious cases, the activity of the adrenal glands is so diminished that you may have difficulty getting out of bed for more than a few hours per day. With each increment of reduction in adrenal function, every organ and system in your body is more profoundly affected. Changes occur in your carbohydrate, protein and fat metabolism, fluid and electrolyte balance, heart and cardiovascular system, and even sex drive. Many other alterations take place at the biochemical and cellular levels in response to and to compensate for the decrease in adrenal hormones that occurs with Adrenal Fatigue. Your body does its best to make up for under-functioning adrenal glands, but it does so at a price.



translation= i'm getting my ass handed to me so i'll copy and paste in the hopes that people won't see me for the retard that i am being proven to be by I ETA PI in this thread.
b

AGB

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Re: MESSAGE TO EPHEDRINE USERS!!!!!!!
« Reply #123 on: April 05, 2008, 12:03:44 AM »
I have seen some differing opinions on the aspirin as preventative medicine. There was some issue with people having heart attacks when dropping it cold turkey. Then there were some issue with potential kidney and liver toxicity with long term use. I think it's like with everything, there are some good effects along with some potentially bad. Who do you think should take a baby aspirin daily?

Do you know of any research showing adrenal damage from ephedrine or other stimulants?

It's not adrenal "damage" you have to worry about with prolonged, ongoing, high dose stimulant use. The adrenals will continue to work well, squeezing gluco-corticoid out with every exogenous stressor. This creates a chronic cortisol state and leads to peripheral insulin resistance. This is why many stimulant abusers of very pro-longed duration, who are concomitantly too fearful of weight regain to take drug holidays, are often left dissatisfied with their long term body composition. Mind you they recount superb results when they first began using stimulants, but now some report backsliding.

For astute followers of clinical endocrinology, you will notice that just about all of the stimulant based obesity medications either slow down, stop, or even revert the rate of weight loss they originally proffered. However, this is not because the stimulant has stopped working, quite the contrary the stimulant is still working, and working well-pumping out glucocorticoid that confers positive feedback on the CNS versus the more conventional negative feedback loop most couch scientists are aware of. And therein lies the quandary.

The weight loss dissatisfaction that is at times seen with long term, chronic, high dose users of stimulants that also constantly require dose escalation, is the result of an evolving metabolic millieu that does not favor body composition in the long run. With each dose they take after day #1 they begin traversing towards an insulin resistant state, which unlike the acute insulin resistance one gets from virginal rhGH use, will hamper fat to lean ration. In fact women who began prescription diet pills in the 70's and never took a break, often times show the same emotional, psychiatric, and physiologic signs and symptoms as those who require glucocorticoid therapy such as prednisone for autoimmune disorders. Even some homology can be drawn, albeit less patently with Cushing's.

Note all of the above specifically addresses those who 1) take stimulants for years and years  2) take ever increasing doses  3) never take drug holidays. Of course, this can all be obviated with judicious dosing, but more importantly, conservative frequency of use.

Now, if there were only some way to throw out the bath water without the baby...


I ETA PI

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Re: MESSAGE TO EPHEDRINE USERS!!!!!!!
« Reply #124 on: April 05, 2008, 03:31:04 AM »
It's not adrenal "damage" you have to worry about with prolonged, ongoing, high dose stimulant use. The adrenals will continue to work well, squeezing gluco-corticoid out with every exogenous stressor. This creates a chronic cortisol state and leads to peripheral insulin resistance. This is why many stimulant abusers of very pro-longed duration, who are concomitantly too fearful of weight regain to take drug holidays, are often left dissatisfied with their long term body composition. Mind you they recount superb results when they first began using stimulants, but now some report backsliding.

For astute followers of clinical endocrinology, you will notice that just about all of the stimulant based obesity medications either slow down, stop, or even revert the rate of weight loss they originally proffered. However, this is not because the stimulant has stopped working, quite the contrary the stimulant is still working, and working well-pumping out glucocorticoid that confers positive feedback on the CNS versus the more conventional negative feedback loop most couch scientists are aware of. And therein lies the quandary.

The weight loss dissatisfaction that is at times seen with long term, chronic, high dose users of stimulants that also constantly require dose escalation, is the result of an evolving metabolic millieu that does not favor body composition in the long run. With each dose they take after day #1 they begin traversing towards an insulin resistant state, which unlike the acute insulin resistance one gets from virginal rhGH use, will hamper fat to lean ration. In fact women who began prescription diet pills in the 70's and never took a break, often times show the same emotional, psychiatric, and physiologic signs and symptoms as those who require glucocorticoid therapy such as prednisone for autoimmune disorders. Even some homology can be drawn, albeit less patently with Cushing's.

Note all of the above specifically addresses those who 1) take stimulants for years and years  2) take ever increasing doses  3) never take drug holidays. Of course, this can all be obviated with judicious dosing, but more importantly, conservative frequency of use.

Now, if there were only some way to throw out the bath water without the baby...



An understanding of physiology here on getbig?
How wonderful to see that comprehension of human science is alive and well! 
AGB, why hast thou stayed quiet for so long?  This post should be force fed to all those attempting to speak with authoritarian tone on subjects they have no clue about.  I'd give you positive rep points if this site were lame enough to have them!