It's pretty well known that progestines in general increase prolactin.
Yeah well I looked at this a while back and couldn't find any data showing this, IIRC Deca might actually lower prolactin. Androgens lower prolactin while estrogens increase it and we know Deca only aromatizes minimally. This is what Nandi/Karl Hoffman said and he was nearly always right.
I don't have a definitive answer to your question about progestins and prolactin, neurotic. In rat studies progestins almost universally lower prolactin. This makes sense because estrogen elevates prolactin, progestins shut down the HPTA, and this results in lowered estrogens and hence lowered prolactin.When estrogen is given to postmenopausal women, prolactin rises; no surprise. When a progestin is added, prolactin falls (1). This all makes sense. But what about in men?One case study showed a large increase in prolactin (2). Another study in cancer patients showed no effect (3). Yet another cancer study showed an increase in prolactin despite a drop in estrogen (4).(1) Maturitas. 1994 Dec;20(2-3):145-50.Antagonism of oestrogen-induced prolactin release by medroxyprogesterone acetate.Castelo-Branco C, Palacios S, Martinez de Osaba MJ, Balasch J, Fortuny A, Vanrell J.(2) Arch Sex Behav. 1990 Aug;19(4):361-72.Medroxyprogesterone acetate, nocturnal penile tumescence, laboratory arousal, and sexual acting out in a male with schizophrenia.Cooper AJ, Losztyn S, Russell NC, Cernovsky Z.(3) Br J Urol. 1990 Mar;65(3):278-81.Effect of high-dose medroxyprogesterone acetate on plasma hormone levels and pain relief in patients with advanced prostatic cancer.Sasagawa I, Satomi S.(4) Scand J Urol Nephrol. 1988;22(1):15-8.Hormonal effects of high dose medroxyprogesterone acetate treatment in males with renal or prostatic adenocarcinoma.Tomic R, Ljungberg B, Damber JE.
How did we go all of a sudden from the data regarding progestins and prolactin in men from being inconclusive to "I remember that you said deca didn't raise prolactin, as a progestin it should, shouldn't it?"I've just never seen any evidence that deca does increase prolactin.
Not on only 200/wk imo. .5mg e3d will probably do the job. Depends how prone you are to aromatization I guess.I don't know about caber. Do some research.
so just 0.5 arimidex EOD would be good enough? (deca 300 and test 200 x 10 weeks).
doing a 10 week cycle, should i start clomid after? or like during week 8 or so?(ps. start that thread tapeworm)
I'm debating about the merits of coming off gradually vs suddenly. Been meaning to start a thread about it.
Tapering off is the old school way of thinking and doesn't really bear any merit IMO. Trab used to swear by this, but it's not something anyone does anymore really since there's no reason to. You could try it and see how you like it, but personally I don't see the need to taper down unless maybe (big maybe) if you've been on for years.
just theorizing here ... i see no point in tapering off the injectables.. BUT, running an oral OR fast acting steroid during the period while your letting those heavy esters drain from your system does make sense to me... that way you can continue gaining, or at least maintaining, all the way up untill you start up your pct drugs.
Running HCG throughout @ 250iu eod with Adex .25mg e4d (lowered from what I started with) on 250mgTE e4d bookended with some var. Pretty mild by most users standards. Will run clomid 50mg/day for a month or as needed afterwards. I'm debating about the merits of coming off gradually vs suddenly. Been meaning to start a thread about it.
Good theorizing there Candy! I will sometimes front load with prop and end the cycle with prop going into PCT. Ive always had good luck doing this.
damn candi,,,how much you spending on your gear??? sounds like you are on everything.i am excited about using human grade shit, much better than BD on anything alin has...
