Define "high" intake. 1,000 I.Us daily? Maybe. 400 I.Us daily? No, only benefits. Just the fact that vitamin E thins the blood is already a huge plus.
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SUCKMYMUSCLE
NO, 400IUS is defined as high and actually increases risk of death like i said. Your statement is patently false.
http://www.hopkinsmedicine.org/press_releases/2004/11_10_04.html"The study results showed that people taking vitamin E supplements of 400 IU or more per day had an increased risk of death."
"Our study results do not support the use of high-dose vitamin E supplements. If people are taking a multivitamin, they should make sure it contains no more than a low dose of vitamin E," said study lead author and internist Edgar R. Miller III, M.D., Ph.D., associate professor of medicine at The Johns Hopkins University School of Medicine. "A lot of people take vitamins because they believe it will benefit their health in the long term and prolong life. But our study shows that use of high-dose vitamin E supplements certainly did not prolong life, but was associated with a higher risk of death."
"In the current study, the Johns Hopkins team re-analyzed raw data from 19 major clinical trials, sorting information by whether high- or low-dose levels of vitamin E were taken. Nine of these studies tested vitamin E alone; 10 tested its use in combination with other vitamins.
The 19 studies took place between 1993 and 2004 and involved more than 136,000 patients in North America, Europe and China. All of the studies involved use of a control group taking a dummy pill, or placebo. Risk of death was estimated by comparing the death rates in both groups. Follow-up periods ranged from 1.4 years to 8.2 years.When the data for these trials was re-evaluated, through a process called a meta-analysis, nine
of 11 trials involving high-dose vitamin E (400 IU per day, or more) showed an increased risk of death. The other eight trials involved low-dose vitamin E users"
when you say vitamin e what exactly are you referring to also? alpha tocopherol, gamma tocopherol perhaps a tocotrienol? they all have different effects to a large degree, and supplementing with one usually decreases plasma levels of the others.