I hoped thought you'd choked on a cake!!
Your comprehension skills are terrible.
As I told you, quit your filibustering attempt to conflate an implied absolute relevancy of rat studies with the, de facto, lack thereof.
Nobody said rat studies per-se are absolutely irrelevant (drugs are tested on rats, nah really?) What was said, was that your rat studies thus far presented are not herein relevent to this example; this by virtue that you have absolutely failed to present a single human study corroborating them, thus you - de facto - vindicate our position.
Or perhaps (and warm up your overly raped asshole once more) you'd like to point to the many drugs that reach phase 5 of drug trials based on the murine pre-clincal phase alone then? LOL ROARING WITH FUCKIN LAUIGHTER, you know-nothing, fucking wet ponce! Did you miss my previous post wherein I declared my previous years working with Merck? But do carry on, wankers like you are the proverbial fish in the barrel LOL
Also, we are discussing Aspartame, so if you could stay on point whilst saving your digressive double talk regarding oro-sensory stimulation, artificial sweeteners and the Cephalic phase of secretion thereof; you are only serving to dig a deeper hole for your fat, virginal self!
For the time being, the money centers on the psychological components of the human equation, but you wont know that, because you are a mongol cunt!
http://www.sciencedirect.com/science/article/pii/S0924224496100479
http://www.sciencedirect.com/science/article/pii/003193849400373D
TO REPEAT: YOU HAVE NO EVIDENCE THAT ASPARTAME ALONE IS INSULINOTROPIC IN HUMANS, NONE!
If you want to present studies employing various food loads and their insulintropic resonance thereafter, then perhaps, dickhead, why not tell folks to stay away from the "allosteric hazard" that is Leucine and Glucose combos. Also, moron, you do realise that glucagon-like peptide 1 is a fucking satiety hormone? More so, you do realise the relevance thereof both these points taken in tandem re: any argument yourself and Mongol Methyl Mike may have been struggling (like cretins) to cobble together? not that that pair of you are spastics you understand!
Now, idiot, human studies with Aspartame, or, and as said, fuck off.
Little boy, you are a wanker pontificating within the walls of a shit forum, take a day off, sonny!
Are you this much of a failure in real life? I bet you're sat there - stained curtains, shit strewn floor - wanking off about my fine tits as you type? squalid little herbert!
Owned by a lowly girl... on a bodybuilding forum no less!!
hahahahahahaha, you are a quirky little boy.
Bwah ha ha ha!!! The Aspartame study clearly states that a drink that
combined sucrose with aspartame elicited more insulin release than a drink that contained sucrose by itself. what does that tell you, idiot? Add the numbers together...that Aspartame clearly elicits insulin release otherwise there would be no difference between the two control groups. Itis not my fault you can't read.
And other sweetners elicit insulin release in Humans, too. Sodium Saccharine elicites release of insulin on Human subjects even by it's taste alone! Whether it is psychological doesen't matter: I never specified the mechanisms by which sweeteners elicit insulin release, only that they do.

So even if the insulin release happens only due to the taste, it doesen't matter as it means I am correct in my assertion.

And studies done on rats are definitely valid on Humans. Why do pharmaceutical companies test drugs intended for Human consumption on rats, you moron? Answer: because posses exactly the same drug receptors, liver enzymes and endocinological processes as Humans. This critique is very, very weak because there are very fw studies performed on Humans on anything since Humans need to volunteer for these trials and there are extremely strict ethical protocols in place when it comes to testing on Humans.
SUCKMYMUSCLE