In the unlikely event that anyone should want to read the articles which W8M8 referenced in her "delightful" post earlier today, I have taked the trouble of including them here.
http://archpsyc.ama-assn.org/cgi/content/extract/66/12/1287
Gene-Environment Interactions
Biologically Valid Pathway or Artifact?
Michael Rutter, MD, FRCPsych, FRS; Anita Thapar, PhD, FRCPsych; Andrew Pickles, PhD
Arch Gen Psychiatry. 2009;66(12):1287-1289.
Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.
JAMA
Interaction Between the Serotonin Transporter Gene (5-HTTLPR), Stressful Life Events, and Risk of Depression: A Meta-analysis
Neil Risch, PhD; Richard Herrell, PhD; Thomas Lehner, PhD; Kung-Yee Liang, PhD; Lindon Eaves, PhD; Josephine Hoh, PhD; Andrea Griem, BS; Marika Kovacs, PhD; Jurg Ott, PhD; Kathleen Ries Merikangas, PhD
Context: Substantial resources are being devoted to identify candidate genes for complex mental and behavioral disorders through inclusion of environmental exposures following the report of an interaction between the serotonin transporter linked polymorphic region (5-HTTLPR) and stressful life events on an increased risk of major depression.
Objective: To conduct a meta-analysis of the interaction between the serotonin transporter gene and stressful life events on depression using both published data and individual-level original data.
Data Sources: Search of PubMed, EMBASE, and PsycINFO databases through March . . .
Genotype-environment interaction in personality development: Indentical twins reared apart:
http://psycnet.apa.org/index.cfm?fa=buy.optionToBuy&id=1989-15146-001
Genotype€nvironment interaction in personality development: Indentical twins reared apart.
By Bergeman, C. S.; Plomin, Robert; McClearn, G. E.; Pedersen, Nancy L.; Friberg, Lars T.
Psychology and Aging, Vol 3(4), Dec 1988, 399-406.
Abstract
The focus of this study is to identify specific genotype–environment (GE) interactions as they contribute to individual differences in personality in later life. In behavioral genetics, GE interaction refers to the possibility that individuals of different genotypes may respond differently to specific environments. A sample of 99 pairs of identical twins reared apart, whose average age is 59 years, has been studied as part of the Swedish Adoption/Twin Study of Aging (SATSA). Hierarchical multiple regression was used to detect interactions between personality and environmental measures after the main effects of genotype and environment were removed. Analyses yield evidence for 11 significant interactions that provide the first evidence for GE interaction in human development using specific environmental measures. Thus, in addition to the main-effect contributions of heredity and environment, GE interactions contribute to individual differences in personality as measured in the second half of the life course. (PsycINFO Database Record (c) 2010 APA, all rights reserved)
Interactions between early parenting and a polymorphism of the child's dopamine transporter gene in predicting future child conduct disorder symptoms:
http://psycnet.apa.org/index.cfm?fa=buy.optionToBuy&id=2010-25857-001
Interactions between early parenting and a polymorphism of the child's dopamine transporter gene in predicting future child conduct disorder symptoms.
By Lahey, Benjamin B.; Rathouz, Paul J.; Lee, Steve S.; Chronis-Tuscano, Andrea; Pelham, William E.; Waldman, Irwin D.; Cook, Edwin H.
Journal of Abnormal Psychology, Vol 120(1), Feb 2011, 33-45.
Abstract
Mounting evidence suggests that genetic risks for mental disorders often interact with the social environment, but most studies still ignore environmental moderation of genetic influences. The authors tested interactions between maternal parenting and the variable number tandem repeat (VNTR) polymorphism in the 3′ untranslated region of the dopamine transporter gene in the child to increase understanding of gene–environment interactions involving early parenting. Participants were part of a 9-year longitudinal study of 4- to 6-year-old children who met criteria for attention-deficit/hyperactivity disorder (ADHD) and demographically matched controls. Maternal parenting was observed during standard mother–child interactions in Wave 1. The child's conduct disorder (CD) symptoms 5–8 years later were measured using separate structured diagnostic interviews of the mother and youth. Controlling for ADHD symptoms and child disruptive behavior during the mother–child interaction, there was a significant inverse relation between levels of both positive and negative parenting at 4–6 years and the number of later CD symptoms, but primarily among children with 2 copies of the 9-repeat allele of the VNTR. The significant interaction with negative parenting was replicated in parent and youth reports of CD symptoms separately. (PsycINFO Database Record (c) 2010 APA, all rights reserved)