Plenty of 450+ lb morbidly obese people with no LIFE THREATENING health issues at roughly 40 years of age....Too much longer and it seems like a lot of minor problems start to gain synergy and compound into much more serious chronic conditions...
350lbs while under 40 is very very manageable with doctor's supervision...Especially when you have thick, heavy set genetics common with Iranians, Iraqis, middle easterners etc...He carries it as well as anyone I've seen..No beet red face or hypertension "look" which is the signal, the beginning of the end, no purple look or overly bad skin conditions, a tell tale sign of liver problems.
I mean if you stayed that big you'd die at 50 no doubt...But for every 10lbs you lost you'd probably add 2 years of life lol..might make 65 if he gets down to 195 HAHA...