The candidate who shall run against her in the big race, needs to have a plan of attack to use at ANY and ALL opportunity. Push her with questions that hit right to the point, to repeatedly knock her off her mountain of lies. If done at a time (such as a "debate") when the media can't ignore or disguise or bury it or whatever, it could do the job it needs to do. The more lines of such attack, the better. The more opportunities to use those attacks, the better.
It is the only way she'll be beaten in an environment where the media is all for her.
The problem comes in if the candidate running against her is just as guilty, because the very last thing that person will do is risk bringing on his own exposure. That's the problem.
That's why Rubio won't do. That's why Cruz won't do.