Having grew up in the Midwest and lived in Florida for 9 years and now being in LA for the last 13 years I can give you my opinion. Most people come to LA with big dreams and hoping to "make it". 99.9% of them don't. They get chewed up and spat out for pretty much every reason you can think of. Since you aren't coming here with big dreams of "making it" and you already have a lucritive job lined up then you'll probably be fine. The people here are indeed girls, but you can find some genuinely incredible people as well. I work in film but on the post side of things so I can easily avoid "the scene" but you can easily wrap yourself into it if you desire. Just be prepared to deal with some of the most disconnected narcissistic human beings you've ever encountered x100.
LA itself, like any big city, has tons of things to do, some of the best food in the country of any type you can imagine and the weather is some of the best in world. Compared to the swampy asshole of the US, Florida, well, there's no comparison. There's tons of opportunity here, there was little affect from the crash in 07, real estate and buying a home here, especially over the last 3 years has gone completely bonkers. Be prepared for a long commute or to get an apartment close to work, which I'd highly suggest if buying isn't an option.
LA is very segregated and despite being one of the most liberal progressive states in the country with the highest taxes there's a TON of poverty and the ghettos of the 60's are still the ghettos of today. The liberal hypocrisy is high here.
Despite all that I wouldn't live anywhere else in the country at this stage. That's not to say I'll stay here for ever, but for now it's home.