Four more years of Trump is highly unlikely, especially now. DeSantis, however has a good chance in either 2024 or 2028, whichever. But the abortion issue, just like the economy (and unlike all the investigations, etc), will not go away because it is an everyday matter which will stay in the news and actually be more and more visible as it gets more and more restricted. This presents a real dilemma for DeSantis. But he’s a clever guy, maybe he will figure out how to walk that tightrope. But life just got a lot more complicated for him yesterday.
DeSantis needs to keep the focus on the economy and many unpopular positions of the Left. But abortion will be an Achilles Heel. A strong pro-life position most likely presents little risk in Florida where he is popular, but it will be a big problem in states like Michigan, Pennsylvania, Nevada, Virginia, etc (even Georgia) in 2024 or 2028, states where he is not well known yet. Just watch him try to skirt around this and change the subject (my prediction)
But, Trump won most of the states you mentioned in 2016, when he flat-out stated, he'd appoint judges who are pro-life and would reverse Roe.
With Biden's utter buffoonery, which will have the Dems getting skinned alive, coupled with Trump handing the right the BIGGEST political win ever, The Donald is quite viable.
We all know that, no matter who the GOP selects, the media will paint him to be Satan-incarnate. A rematch in 2024 would be president vs president. Biden has squandered virtually all the good will he had (deservedly so or not), when it came to handling coronavirus, the economy, or bringing the country back to "normal".
And Trump crushes everybody else the Dems can put up, if they decide to abandon Sleepy Joe.