Anybody else have Familial Hypercholesterolemia?

[Gym Rat]

what were your numbers like?

Which numbers, the Calcium score?  Mine was almost 400, which they say is high.
But all the follow-ups showed there were a lot of tiny spots, that added up to that total.
Nothing substantial in one spot. Follow-up tests showed all-clear, zero blockages, etc.

Statins calcified plaque spots, protecting it from rupture.

When I was an 18-year old, ripped as BHanks, my cholesterol total was right around 300.
My HDL was very very high. Only issue so was LDL and Triglycerides. (Blood fats).
Familial issue for sure. (Father died at age 47, heart disease, etc). So runs in the family.
Im one of the cases where statins help and are needed. Only problem is that they way over-prescribe them.

When risk-ratio is below 3.5 or so, they are not really needed.

Risk ratio =Total cholesterol / HDL . Even with that they are probably just guessing. No exact science for it..

[IroNat]

My cholesterol was 267.

I too ate a clean diet, maintained a healthy weight and exercised everyday. High cholesterol runs in my family.

Instead of posting on Getbig and asking for advice I talked to my family Doctor.

Now my cholesterol is a healthy 160.

Be careful whose advice you take. Especially when it comes to your health.

 

How silly.

[Matt]

Yup, that is also a subject not fully understood.
Calcification of plaque is also protective, prevents ruptures. You can have tiny spots of calcium, in a lot of places, which all add up for a score that initially appears high.
(And have zero blockages).

Lots who say "I have zero calcium score" end up having soft-plaque and blockages, and bypasses.
The test cant see the real dangerous stuff (soft plaque).

Its good to get the test, if you have any, it triggers all of the needed invasive tests to see if there's any danger/blockages.

Wow. That's nice to know that one test can trump all other tests like that - especially the invasive ones.

I know as I went thru it all. In the end, some calcium, zero blockages, and 65% ejection-fraction which is tops for my age group.

One thing statins may do for people (who need them) is to calcify soft plaque and prevent rupture...

Can you have a 100% ejection fraction?

[Gym Rat]

Wow. That's nice to know that one test can trump all other tests like that - especially the invasive ones.

Can you have a 100% ejection fraction?

No... Otherwise all of the blood would be pumped out of the ventricle (not good).
When I first heard 65% I was like "WTF" then they explained it that its a top number.

-----------

Ejection fraction is a measurement of the percentage of blood leaving the heart each time it squeezes. When the heart squeezes, it's called a contraction. Ejection fraction is just one of many tests your health care provider may use to see how your heart works.

The heart contracts and relaxes. When the heart contracts, it pumps out — ejects — blood from the two lower heart chambers, called ventricles. When the heart relaxes, the ventricles refill with blood. No matter how forceful the contraction, the heart can never pump all (100%) the blood out of a ventricle. The term "ejection fraction" is the amount of blood — as a percentage — that's pumped out of a filled ventricle with each heartbeat.

The ejection fraction is usually measured only in the left ventricle. The left ventricle is the heart's main pumping chamber. It pumps oxygen-rich blood up into the body's main artery, called the aorta. The blood then goes to the rest of the body.

According to the American Heart Association:

A left ventricle (LV) ejection fraction of about 50% to 70% is categorized as normal.
A mildly reduced LV ejection fraction is usually between 41% and 49%.
A reduced LV ejection fraction is usually 40% or less.

[Matt]

Thanks Gym Rat!

Do you know what John Meadows' ejection fraction was?

Antoine Vaillant - 2013 vs. 2020:

[jwb]

Which numbers, the Calcium score?  Mine was almost 400, which they say is high.
But all the follow-ups showed there were a lot of tiny spots, that added up to that total.
Nothing substantial in one spot. Follow-up tests showed all-clear, zero blockages, etc.

Statins calcified plaque spots, protecting it from rupture.

When I was an 18-year old, ripped as BHanks, my cholesterol total was right around 300.
My HDL was very very high. Only issue so was LDL and Triglycerides. (Blood fats).
Familial issue for sure. (Father died at age 47, heart disease, etc). So runs in the family.
Im one of the cases where statins help and are needed. Only problem is that they way over-prescribe them.

When risk-ratio is below 3.5 or so, they are not really needed.

Risk ratio =Total cholesterol / HDL . Even with that they are probably just guessing. No exact science for it..

my calcium score was 5 and only showed in one artery, the rest were zero.

Most males in my family die young from cancer or suicide so don’t have much to go on as far as heart disease. The women live very long lives.

So, were you on a statin for a short time to hard it up and then stopped?

[joswift]

my calcium score was 5 and only showed in one artery, the rest were zero.

Most males in my family die young from cancer or suicide so don’t have much to go on as far as heart disease. The women live very long lives.

So we’re you on a statin for a short time to hard it up and then stopped?

you should transition...

[jwb]

you should transition...

probably get breast cancer 

[GymnJuice]

Wow. That's nice to know that one test can trump all other tests like that - especially the invasive ones.

Can you have a 100% ejection fraction?

No

[Gym Rat]

my calcium score was 5 and only showed in one artery, the rest were zero.

Most males in my family die young from cancer or suicide so don’t have much to go on as far as heart disease. The women live very long lives.

So, were you on a statin for a short time to hard it up and then stopped?

I've been on low-dose simvastatin (10 mg) since I turned 40 (16 yrs).
I feel no sides from it... (They tend to show up more at higher doses, like most drugs).

[OAK]

I've been on low-dose simvastatin (10 mg) since I turned 40 (16 yrs).
I feel no sides from it... (They tend to show up more at higher doses, like most drugs).

Wow.

You've been on statins for 16 years you say?

You must be EXTREMELY trusting of Big Pharma and the Medical System.

 

[jwb]

I've been on low-dose simvastatin (10 mg) since I turned 40 (16 yrs).
I feel no sides from it... (They tend to show up more at higher doses, like most drugs).

seems like a low dose isn’t too hard to handle.

What is you LDL, HDL and trigs now?

[affeman]

[Gym Rat]

seems like a low dose isn’t too hard to handle.

What is you LDL, HDL and trigs now?

Just had bloods the other day.

186 total
51 HDL
113 LDL
76 Trig's

4.2 ratio

---------

Not where things should be in most Doc's eyes, but fine...

6 months ago things were a little lower all around, LDL was 99, but HDL was 39. (I experiment with red yeast rice, niacin dose and other things as well).
Numbers like these arent a concern...

They try to program people to get it in range "OR ELSE". My Doc is smarter than that.
(A bit bummed he told me he's retiring, after 18 years I need to find another).

[Gym Rat]

Wow.

You've been on statins for 16 years you say?

You must be EXTREMELY trusting of Big Pharma and the Medical System.

 

I dont recall statins killing young athletes...
Plus I know what I need, and the clot-shot, yup.. Not needed...

I buy all my own meds (India) and do my own Rx as well.
(And bloodwork). Its actually cheaper than USA w/ Insurance.

He only checks it once a year with my yearly physical.
I go 3-4 times a year for my own bloodwork and I adjust as I feel I need.

So yeah, no one really tells me what to take... (Unlike Sheep)

[Gym Rat]

Wow.

You've been on statins for 16 years you say?

You must be EXTREMELY trusting of Big Pharma and the Medical System.

 

The other thing is big-pharma isnt needed for Monacolin-K, they stole it.
Used in China for a million years.  Other countries, still OTC.

All statins are synthetic forms of Monacolin-K (natural fermented lovastatin made with yeast and rice).
So yeah, not real trusting of it (was never un-trusting until the fake scamdemic actually).

Most folks know how to critically think, unlike Sheep. Take a known-safe substance used in Asia for a million years or a rushed to market "cash grab" thats killing people.
Hmmm... Let me see if I can tell the difference. 

[jwb]

Just had bloods the other day.

186 total
51 HDL
113 LDL
76 Trig's

4.2 ratio

---------

Not where things should be in most Doc's eyes, but fine...

6 months ago things were a little lower all around, LDL was 99, but HDL was 39. (I experiment with red yeast rice, niacin dose and other things as well).
Numbers like these arent a concern...

They try to program people to get it in range "OR ELSE". My Doc is smarter than that.
(A bit bummed he told me he's retiring, after 18 years I need to find another).

Nice numbers…. LDL of 100-150 would make me comfortable…. 230 is too high even with my other numbers being so good, but going under 100 like some people insist seems just as dangerous as too high…

[nzgs]

I am pretty lean, eat very well, have high HDL and low Triglycerides and my Calcium heart score is less than 5, yet my total cholesterol is now over 300.

Anyone else have FH and what has been your experience and treatments etc?

I have never done gear either btw…

High total cholesterol is healthy. LDL isn't "bad". It's bad when vLDL becomes inflamed which is rather different, and it's bad to have such chronic inflammation that your arteries are constantly being repaired with cholesterol. I would look into "lean mass hyper responders" since you seem to fit that profile.

Ideally people should have high total cholesterol, high HDL:Trig ratio, low CAC score, low inflammation biomarkers. This is pretty much the opposite of "mainstream" old fashioned advice which is that it doesn't matter how bad your biomarkers are so long as LDL is low, which is dangerous advice.

[IroNat]

Can you have a 100% ejection fraction?

Are you talking about the heart or...

[robcguns]

My dads cholesterol is in the 600s and has been for 40 years, also has triglycerides in the 2-3000. Never taken a statin and eats Mayo sandwiches. He’s 73.

[wes]

My dads cholesterol is in the 600s and has been for 40 years, also has triglycerides in the 2-3000. Never taken a statin and eats Mayo sandwiches. He’s 73.

When I was a kid we lived on Mayo sandwiches so we could save enough money for our annual ski trip to the Swiss Alps! 

[IroNat]

When I was a kid we lived on Mayo sandwiches so we could save enough money for our annual ski trip to the Swiss Alps! 

[IroNat]

My dads cholesterol is in the 600s and has been for 40 years, also has triglycerides in the 2-3000. Never taken a statin and eats Mayo sandwiches. He’s 73.

That's wild Rob.

But I doubt your father will live to 120.

[ChristopherA]

Were you feeling bad or you just caught this on a routine checkup? I never go to the Dr

[Gym Rat]

My dads cholesterol is in the 600s and has been for 40 years, also has triglycerides in the 2-3000. Never taken a statin and eats Mayo sandwiches. He’s 73.

Legend!