From my readings donating blood is also risky in some aspects. I wouldn't do therapy, but I'm not a doc so... I would take the supplement nattokinase. Read up on it. Doctors aren't sure if high levels affect mortality when due to hrt, they do it as "just in case," or some endos don't maybe believe that much but I don't know. I'm not sure if those who live at high altitute are also at risk but I have read "no."