Is he suspected to be involved or are you just saying morally he should resign?
Based off memory it was his best friends wife.
It was suicide so no I don't think he killed her. Did his affair contribute to her state of mind? I say yes. He's a public figure. I don't think we need any kind of purity test for people, but there are certain lines that shouldn't be crossed, like banging your young married staff member while you are married with six kids, and the staff member then lights herself on fire. No way should this guy be a U.S. Congressman.
Regarding Newsom, it was his campaign manager's wife. That's not just best friend, but like a brother.