A pro for compound-exercises is the fact that it is synergistic. There's only a small chance that other bodyparts grow out of proportions.
If you
only measure the effectiveness on the muscle that you want to target there will be a small difference between isolation and compound,
yet using compound will give you a more complete workout cause you workout smaller muscles that aren't stimulated by isolation-exercises. The famous difference between an ordinary lever-press and the classic benchpress. In the contrary, somebody who's always used to bench-press hasn't got a really big problem with lever-press. That's a simple fact.
That's also the problem with so-called research, it's very difficult to measure the cumulation of active muscles that you use with free weights, the conclusion
effectiveness isolation = effectiveness compound
is wrong.
A contra using a lot of compound in combination with a bad routine is a bigger chance on overtraining.
Fe today a lot of benchpress and tomorrow triceps isn't an optimal routine.