Advil is Ibuprofen, which similar to Aspirin and Indocin are a class of drugs known as Non-Steroidal Anti-Inflammatory Drugs (or NSAIDS).
They all work by inhibiting various parts of the Cyclo-oxegenase pathways (the pathway responsible for the inflammatory response in the body) to decrease inflammation.
Unfortunately the NS in NSAIDS, could also stand for NON - SELECTIVE...they have a variety of other effects including:
1) Disrupting the prostaglandin lining of the stomach inducing ulcer or preventing ulcers from healing
2) Inhibiting the primary hemostatic pathway (platelet function)
3) Affecting the Efferent glomerulus of the Kidney to increase BP and also can cause interstitial nephritis and allergic nephritis (progressing to renal failure) if taken in excess.
So basically, yeah, he probably did get renal failure from abusing NSAIDS and also from the diuretics he took....i'm not sure if the huge protein intake had an impact (but it certainly did not help).
Maybe Nicorulez could speak on whether the protein may have an effect.
In summary,
I'm glad we're all smart enough to know that roids aren't the culprit of all these bodybuilder deaths and liver and kidney problems. So up the dose and hope for the most! Hi Tom Prince
Monster Logic