I am getting a cortisone shot in my back to reduce some inflammation. How does cortisone effect your body as far as bodybuilding? I know it breaks down muscel tissue and can make you hold water...
but.. does one cortisone shot throw you off that much?

??
what are the side effects as far as bodyfat, musclebreakdown or water weight gain???
I wouldn't worry about that at all. I'd try to stay away from going to the shot unless you've tried everything else and this is the only way. lots of the time the doc will say come back in 2-4 months if there is a problem again, don't go back unless you HAVE to. Personally I've never had the shot, but i've talked to alot who have and they all say it should be your last resort.