Wrong. You claimed that there are studies showing vitamin E to increase the rate of death. I said I've been taking vitamin daily for 10 years and I haven't died yet. My blood work shows a great lipoprotein profile, and my liver enzymes and kidney function is superb. My personal experience can be seen as a scientific study that contradicts the ones you pointed out. Why? Because vitamin E is the only supplement I've taken daily for ten years, so there are no extraneous variables that could mitigate the deleterious effect of vitamin E - if there are any, which my scientific study on myself proves there is none. I also know people who have taken up to 1,000 international units of vitamin E daily for 25 years who have superb health - but since they also took several different supplements, I won't use them to prove my point. 
No, caffeine is synthesized by several species of plants precisely to kill pests that feed on them. It is not required by any living organism at any dose, and it is harmful at any reasonable dose - unlike water, which is required for life. Don't argue that it not harmful at, say, one miligram because then the argument becomes reductio ad absurdum and I won't go there. Even a dose as low as 30 miligrams of caffeine can cause momentary hyperglycemia enough to harm a severe diabetic. In Humans, caffeine blocks adenosine in the brain disrupting the body's circadian rythm. It causes the release of epinephrine from the adrenal glands, leading to hyperglycemia and an increase of corticosteroids, which are terrible for the skeletal muscles, CNS and even disrupts the digestive and excretory system - although much less dramatically than much stronger sympathomimetic agents like amphetamines. Prove to me that caffeine is not a poison. You can't! The definition of poison is that of a substance that is not required to sustain life and is disrupts the body's physiological funtioning. Going by your logic, even breathing too hard for too long can kill you. That is an absolutely terrible definition for what a poison is.
What definition? Yours? The difference is that water is required for remaining alive. That is why it is not a poison. Going by your absurd logic, even oxygen is a poison since breathing too hard for too long might kill you. How can you compare water, a substance that the average Human needs to ingest at least one liter a day to remain alive, to a subtance that wll kill you at a dose roughly one hundred times smaller - 10 grams or so. So yes, everything can be a poison, but elements that are required for remaining alive only become poisonous after a certain dose, whilst susbstances such as alkaloids like caffeine don't add anything good for the body at any dose.
Yes, I do. And?
What are your qualifications? You are not even a medical doctor like you make yourself appear to be. From what I recall, you dropped out of medical school, didn't you?
SUCKMYMUSCLE
"Wrong. You claimed that there are studies showing vitamin E to increase the rate of death. I said I've been taking vitamin daily for 10 years and I haven't died yet. My blood work shows a great lipoprotein profile, and my liver enzymes and kidney function is superb. My personal experience can be seen as a scientific study that contradicts the ones you pointed out. Why? Because vitamin E is the only supplement I've taken daily for ten years, so there are no extraneous variables that could mitigate the deleterious effect of vitamin E - if there are any, which my scientific study on myself proves there is none. I also know people who have taken up to 1,000 international units of vitamin E daily for 25 years who have superb health - but since they also took several different supplements, I won't use them to prove my point.

"
this is the very opposite of the scientific method, so the pure idiocy of this post cannot be overstated. Do you realize that you have no controls, no statistically analysis, nothing resembling
"No, caffeine is synthesized by several species of plants
precisely to kill pests that feed on them. It is not required by any living organism at any dose, and it is harmful at any reasonable dose - unlike water, which is required for life. Don't argue that it not harmful at, say, one miligram because then the argument becomes reductio ad absurdum and I won't go there. Even a dose as low as 30 miligrams of caffeine can cause momentary hyperglycemia enough to harm a severe diabetic. In Humans, caffeine blocks adenosine in the brain disrupting the body's circadian rythm. It causes the release of epinephrine from the adrenal glands, leading to hyperglycemia and an increase of corticosteroids, which are terrible for the skeletal muscles, CNS and even disrupts the digestive and excretory system - although much less dramatically than much stronger sympathomimetic agents like amphetamines. Prove to me that caffeine is not a poison. You can't! The definition of poison is that of a substance that is not required to sustain life and is disrupts the body's physiological funtioning. Going by your logic, even breathing too hard for too long can kill you. That is an absolutely terrible definition for what a poison is.
What definition? Yours? The difference is that water is required for remaining alive. That is why it is not a poison. Going by your absurd logic, even oxygen is a poison since breathing too hard for too long might kill you. How can you compare water, a substance that the average Human needs to ingest at least one liter a day to remain alive, to a subtance that wll kill you at a dose roughly one hundred times smaller - 10 grams or so. So yes, everything can be a poison, but elements that are required for remaining alive only become poisonous after a certain dose, whilst susbstances such as alkaloids like caffeine don't add anything good for the body at any dose. "
if you had a modicum of reading comprehension you would realize i said what defintion? there are a couple. According to the father of modern toxicology you are wrong. If you excluding essential nutrients from being poisons that makes no sense according to the widely used definition of substance which does harm to the organism.