bodybuilding.com http://www.bodybuilding.com/store/glutamine.html
dude give up dont try and win at this one
Gee, now that's a GREAT source of information!! LOL A website that sells, among other things, glutamine products. Naw, they wouldn't be biased at ALL!!!!!
I ask you to provide specific scientific studies showing the muscle building effects of glutamine supplementation from peer reviewed journals. And this is what you come up with? A write up from some hack on bodybuilding.com? That's not going to convince anyone who doesn't buy into the marketing hype of supplements.
Here's what Lyle McDonald (well known researcher and diet guru) has said about glutamine:
"a. There was that one study whree only 2 grams of glutamine raised GH; how relevant this is is hugely debatable. I seem to recall seeing it argued that small amounts of glutamine somehow avoided 'activating' GI uptake so it was possible to sneak some through that way. Or you could take monster dose and just get it through via mass action. Maybe if you wanna take a bottle per day or something.
b. Most of the anabolic glutamine work was in vitro. Put it into a cell and it increases protein synthesis. Two huge problems:
1. Most oral glutamine won't get there
2. There is a HUGE concentration gradient problem with the direction of flow being from inside the muscle cell out. I saw an infusion paper once showing that even infused glutamine couldn't raise intracellular concentrations of glutamine in muscle. No way is oral glutamine going to do it.
About the only way that oral glutamine might impact on muscular glutamine stores would be super indirectly. More or less we have a system of
gut <-> liver <-> blood stream <- skeletal muscle
in terms of how glutamine can flow (and the gut to bloodstream path is limited).
But consider a situation where the gut is using a lot of glutamine for some reason.
IF (and this is a big if) you weren't getting enough in the diet, you might end up seeing a drop in skeletal muscle glutamine stores because it's being pulled out to fuel other tissues.
Providing the gut with plenty (and this is under an immune system challenge or something traumatic like a burn victim) *might* prevent a drop in skeletal muscle concentrations."