complete bullshit. Short esters are superior to long esters in every way, minus injection frequency.
Really? Care to cite a study to back you up? Because I will back up my claims with a reference if you wish to debate further. Oh, nevermind. Here's the study.
In one study, scientists compared an injection of Testosterone Propionate with Testosterone Enanthate, and they found that the injection of testosterone propionate resulted in nitrogen retention of 1.02g/day with a total measurable anabolic activity of 12 days, while the Enanthate version resulted in nitrogen retention of 1.76g/day and had a total measurable anabolic activity of 33 days.
Look it up if you want to satisfy yourself.
Reifenstein, et. al. Studies comparing the effects of certain testosterone esters in man.J Am Geriatr Soc. 1954 May;2(5):293-8.. PMID: 13162731
Here's two more nandrolone ester related topics:
Chaudry, M.A.Q.; James, K.C.; et al. J. Pharm. Pharmac., 1976, 28, 882-885
Chaudry, M.A.Q.; James, K.C. J. Med. Chem., 1974, 17, 157-161.
I'll also add some basic first year pharmacology to the mix. Endocrinologists know that injecting a hormone variant will produce a longer half-life in the body than having a patient take the same variant orally. We know this, because blood hormone concentrations don't have the same severe peaks and valleys. The blood concentrations stay more stable. We also know that if you add hydrophobic properties to an injected drug, you draw out the activity of the injected drug even more. Hydrophobic activity prevents hydrophillic esterase enzymes from interacting with the drug, thus delaying its release. The longer the release, the more even keeled the drug concentration, the more manageable the results/interactions, etc...in short, more good, less bad.
Now, you are correct in terms of two things bodybuilders hate most:
1. water rentention
2. estrogen production (assuming we're talking about drugs that can convert to an active estrogen)
When it comes down to it, longer esters produce higher levels of estrogens than do shorter esters. And it's the estrogen that bloats us up with water. But that water and bloat also has a benefit. Studies also show that some estrogen conversion is necessary to maximize the body's production of GH and IGF-1 in response to steroid use. So it's not black and white. Like all hormone use...lots of grey.
Journal of Andrology, Vol. 24, No. 5, September/October 2003 Copyright © American Society of Andrology Pharmacokinetics and Degree of Aromatization Rather Than Total Dose of Different Preparations Determine the Effects of Testosterone: A Nonhuman Primate Study in Macaca fascicularisGERHARD F. WEINBAUER*, CARL-JOACHIM PARTSCH, MICHAEL ZITZMANN, STEFAN SCHLATT AND EBERHARD NIESCHLAG
And that Andrology study also showed that short-acting esters had less of an affect on the testes and gonadal sperm production (mind you, this was very short term dosing. You use prop long enough and enough of it, and you'll shut stuff down well enough).
I'm not saying prop or acetate esters are bad, and I think pure test suspension definitely has a place and time. In some instances, they would be preferable to long esters, such as in athletes being tested. But long esters provide greater anabolic activity, and that's been proven. And I will hazard a guess that most guys use steroids for building muscle size first and foremost, and that anabolic activity is the chief concern regardless of half-lives. If you can get past the sie-effects of testicular shut-down and some bloating, you'll simply build more muscle with longer esters.
Come near a show, I wouldn't doubt shifting to shorter esters is better for reducing water retention. But if you're not getting show ready, a bit of bloat is good for the body.
If that's you in your avatar, you're better than I am. You obviously know what works for you, and that's worth more than any of my pharmacology rants...I won't argue that with you. You know what works for you, and that's the most important thing a bodybuilder can do. But you probably shouldn't make absolute statements about applying what works for you to everyone on the board. Plenty of kids read these boards and will believe anything a guy like you says because of how you look. So just be careful...
I'm only arguing on a pharmacology and metabolic response level. You made a pretty bold and absolute statement, and I'm trying to pass along a bit of knowledge on the boards. Too much bro science when it comes to drugs.