OTOH, you can achieve higher peak levels with short esters, particularly if shot less frequent than ideal for stable levels. Say if you did 300mg of tren ace every 3rd day, instead of 100mg per day.
This could lead to more gene activation even if total weekly dose is the same... you know what I'm getting at? Just an idea I've been floating recently.
Interesting, for sure. You know your stuff.
I guess you could try to rationalize with a thought exercise: assume your liver won't melt by doing this, first off. But if you had to bet money on it, which would you choose: 7 anadrols in one day and off for six, or 1 anadrol per day for 7 days?
I wonder if the short-term mega spikes will be enough to create the constant anabolic environment needed. Not to re-hash my old posts, but when the drug concentration is more constant in the bloodstream, there's a stronger anabolic effect and net nitrogen retention, mg for mg (at least when we compare testosterone...not sure we can't say the same, necessarily, for a DHT derivative or 19 nor derivative because I haven't seen the research, though we may wish to assume). That said, you're right - it's all about gene activation. You saturate receptors and hammer the shit out of them with a mega dose and they don't have room to breathe...they're constantly bound. But, does the body over-compensate to the heavy load by clearing the drug out faster? Can it reasonably do that?
It would be an interesting study to say the least.
Didn't Borresson (sp?) buy into the huge spike theory? Not sure if you've read his stuff, or if I understand his old theories correctly.
