I use to hear Bill Pearl say don't train to failure all the time. I thought he was nuts but he is right on target. He basically said no one can train to failure without quitting due to exhaustion to give yourself a break. Olympic lifters and Power lifters cycle their training to the that one or two rep failure. Why do bodybuilders think every lift has to be to the red line of the tach? Bill Pearl even said if you are doing your sets and you don't hit your rep goal lower the weight. In the HIT world that is blasphemy. I'm a worth ethic driven person and the Mentzer/Jones just played into my misguided mentality.
Basile what you wrote, " Big muscles are good for doing lots of sets with a reasonable resistance. So that is exactly how you have to train for hypertrophy" hits it on the head. A bodybuilding muscle for lack of a better term is for muscular endurance. Not to be confused with cardio endurance.