Sound advice right there. I liked John, but in one of his videos, he said TRT for him was 500mg. Insanity. Anything 200mg or more is too much. I had an SHBG of 70 and 160mg was more than enough free test (30ng/dl before injection day), and I eventually lowered the dose and started donating blood because of hematocrit.
Sheesh - and of course, that level would not be prescribed by his Doctor, so he's self 'medicating' at this point
I don't suppose he mentioned what with..? Is it usually cypionate? I'll confess to not knowing much about HRT, but as I get older I'm getting more and more intredasted for some reason

You sure he said 500mg after his heart attack? I'm almost positive he didn't say that? I want to say it was 100mg, maybe 200mg for a while but he didn't say 500mg anywhere from what I saw. You could tell his heart issues had him rattled, I mean part of his heart was dead and not moving.
Aromasin is a lot better on ldl than arimidex, many can be on trt and depending on genetics not convert much to estrogen, some not so fortunate.
Nolvadex isn't an aromatase inhibitor, it's actually an estrogen so it doesn't affect cholesterol the same as an AI. But it does possibly have that blood clot side.
From what I gather estrogen is actually protective of the CV system and more and more HRT docs don't touch it, let it go as high as it does naturally. Estrogen is good.
Speaking of high dosages when you get older, I have a good friend who is 57 years old and his baseline self-administred HRT (lol) is 1,000mg. Then he adds stuff cyclically. Say 600mg of Deca or a gram of EQ, or a couple of Anadrols or all of these at the same time. He just told me he got off Anadrol - had been on for over a year. His hematocrit did run high but otherwise his blood work has been ok. But this isn't safe of course.