If it was muscle pains you could consider a reattempt with adding coenzyme q10 to an alternative statin. Some people can tolerate one statin but not another. Usually pravastatin or pitavastatin are better tolerated than rosuvastatin or atorvastatin. The injectable medications are expensive and usually not covered by insurance unless you've had a stent or a bypass (but should have less risk of muscle pains).
If the indication was for treatment of high cholesterol without having had heart disease or strokes it's understandable you might not want to risk the side effects. With my family history I was more concerned about heart disease than potential dementia or muscle pains so I am pretty aggressive with minimizing cardiac risks (along with lifestyle modifications, diet, exercise etc).
I was on low dose simva for a long time. Bloodwork pre Covid was stellar.
In 2020, it went a bit haywire. Still unsure why, but I went from a total of 175 up to 300. I was eating more meat, but that's a huge spike.
New cardio doc put me on rosu, and it dropped to 200 pretty quickly, without dietary changes. Muscle cramps and spasm were too much - I have always supplemented COQ10 during all these.
Moved me to prava 40mg and it went back up to the 250 range. So he went to prava 80 + ezetimibe. I have to get lipid panel in a week.
I also told him if I'm going to stay on the drugs and up the dose, I'm also going to restrict sat fat to less than 10g most days. Also started running more because that was the only thing that ever raised my good cholesterol.
I am aware of the trig ratios, apob and all the other tests. My apoB test was fine. I am also aware of all the arguments on both sides of the statin coin. I am following the doc right now to see.
I may get a full genetic panel evaluation if my numbers aren't good. I really want to get to the root cause of what changed post pandemic. I do know I did a shit ton more running back then, but unsure of the effect.