Gore is a stud but he doesn't score touchdowns that often. Depending on the point- scoring in league play, you want a running back who has a nose for the goaline and Gore hasn't scored more than 8 Td's in one season, I think(rushing only). Yards and receptions score points in some fantasy league but touchdowns are what counts in fantasy football.
I would stay away from Gore because opponents will be stacking eight in the box against him. Defenses won't respect the 49er's passing attack so they'll focus on Gore, which will limit his productivity.
Most or all fantasy people who prefer to draft players from their favorite team end up losing in their drafts. You have to look past your favorite players and draft wisely. There's this guy in my league who is a HUGE Saints fan. Three out of his first six picks are always Saints players and he continues to finish at the bottom of the league year after year. I wonder why. I'm not saying you do that, Beach but Gore is not even in the top eight in fantasy running backs this year. Top eight represents 1/4 quarter of the number of teams in the NFL, so do the math.
I don't rank players based on whether they play on my favorite team. My analysis of Gore has nothing to do with him being a Niner. (But I do refuse to draft Dallas Cowboys, just as a matter of principle.

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Teams won't do anything differently than they did in 06, when Smith started the whole season and stunk up the field.
I play in NFL.com leagues. One point for every ten yards rushing/receiving and six for TDs.
I haven't ranked anyone yet, but give me your top 10 RBs for 08. I guarantee you there are question marks about everyone except LT and possibly Westbrook.